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Match the following hypersensitivity reactions with the associated immune response or disease
1. IgE mediated
2. Poison ivy
3. Blood transfusion reaction
4. Associated with autoantigens
5. Immune-complex mediated
6. Allergies (e.g. hay fever)
7. IgG or IgM mediated
8. Cell-mediated
Type I
Type II
Type III
Type IV
Step by step
Solved in 3 steps
- Match the immunity concept with the best description. ___anaphylactic shock a. recognizes antigen ___immune memory b. inadequate immune response ___autoimmunity c general defense mechanism ___inflammation d. immune response against ones own body ___immune deficiency e. secondary response ___antigen receptor f. acute allergic reaction ___antigen processing g. presenting antigen together with MHC markersType I (immediate) hypersensitivity A. is mediated by IgE B. is mediated by T lymphocytes C. both is mediated by IgE and involves degranulation of mast cells D. involves degranulation of mast cellsType ___ hypersensitivity reactions are also called delayed-type hypersensitivity. I II III IV Type___ hypersensitivity reactions are typically observed after drug-induced hemolytic anemia or thrombocytopenia. I II III IV 3. Type ___ hypersensitivity reactions involve the rapid triggering of mast cell degranulation. I II III IV
- Which of the following is false about HLA class I molecules? A. They are encoded by multiple and highly polymorphic genes. B. They consist of alpha and beta chains. C. They possess beta-2 microglobulin. D. They present foreign antigens to cytotoxic T cells. E. none of the aboveIf the thymus of an adult experimental animal is removed, the following observations can be made: (a) No immediate effect occurs, and (b) after 1 year, decreases occur in the number of lymphocytes in the blood, the ability to reject grafts, and the ability to produce antibodies. Explain these observations.Which type of hypersensitivity involves solubleantigen-antibody complexes?a. type Ib. type IIc. type IIId. type IV
- Which ONE of the following is TRUE regarding adult T‐cell leukaemia‐lymphoma? Select one: A.The tumour cells have a CD4+ CD25+ phenotype B.It is usually cured with the CHOP chemotherapy regimen C.It is most commonly caused by infection with HIV D.It is commonly associated with hypocalcaemia at presentationThe classic clinical problem with immunodeficiency disorders is the development of which of the following? (A) hypotension (B) the Rh factor (C) organ rejection (D) severe infectionsMaternal antibodies transmitted via the placenta: A. are an example of natural passive immunity B. are an example of natural active immunity C. are IgG antibodies D. both are IgG antibodies and are an example of natural active immunity E. both are IgG antibodies and are an example of natural passive immunity
- Why must antibody treatments like ZMapp be composed of monoclonal antibodies instead of polyclonal antibodies? a. Therapeutic antibodies must all bind the same epitope. b. Therapeutic antibodies must NOT all bind the same epitope. c. Monoclonal antibodies have much higher binding affinity than polyclonal antibodies. d. Monoclonal antibodies have much lower binding affinity than polyclonal antibodies. e. Monoclonal antibodies can be produced indefinitely; polyclonal antibodies can only be produced for a short time. IS it B? Can you please explainWhich of the following is a non-organ-specific (systemic) autoimmune disease? a. Systemic lupus erythematosus (SLE) b. Hashimoto's thyroiditis (hypothyroidism) C. Graves' disease (hyperthyroidism) d. Insulin-dependent diabetes mellitus (Type I diabetes)Which of the following statements is NOT true of a fever?a. Temperature is regulated by chemicals that reset the body's thermostat to a higher setting.b. The higher than normal body temperature impairs the functions of some bacteria.c. The higher than normal body temperature is always harmful.d. The higher temperature impairs leukocytes andantibody production.e. Both c and d. Which of the following statements is NOT true of antibodies?a. They bind to foreign antigens, making them susceptible to being engulfed by phagocytes.b. They serve as specific binding sites on B cells.c. An antibody is usually able to bind to a variety of different types of antigensd. They are composed of two heavy chains and two light chains.
