hypothyroxinemia in premature infants is a cause of subsequent motor and cognitive abnormalities [16]. Blood thyroxine values were obtained on routine screening in the first week of life from 536 infants who weighed 2000 g or less at birth and were born at 33 weeks gestatic or earlier. The data in Table 11.21 were presented concerning the relationship between mean thyroxine level and gestational age. Hint: 10 10 10 Σx-255, ΣΥ-8205, Ση-75.4

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TABLE 11.21 Relationship between mean
thyroxine level and gestational age
among 536 premature infants
()
Gestational age
(weeks)
Mean thyroxine level
(ug/dL)
<24
6.5
25
7.1
26
7.0
27
7.1
28
7.2
29
7.1
30
8.1
31
8.7
32
9.5
33
10.1
Treated as 24 in subsequent analyses.
Transcribed Image Text:TABLE 11.21 Relationship between mean thyroxine level and gestational age among 536 premature infants () Gestational age (weeks) Mean thyroxine level (ug/dL) <24 6.5 25 7.1 26 7.0 27 7.1 28 7.2 29 7.1 30 8.1 31 8.7 32 9.5 33 10.1 Treated as 24 in subsequent analyses.
4. Transient hypothyroxinemia, a common finding in premature infants, is not thought to have long-
term consequences or to require treatment. A study was performed to investigate whether
hypothyroxinemia in premature infants is a cause of subsequent motor and cognitive
abnormalities [16]. Blood thyroxine values were obtained on routine screening in the first week
of life from 536 infants who weighed 2000 g or less at birth and were born at 33 weeks gestation
or earlier. The data in Table 11.21 were presented concerning the relationship between mean
thyroxine level and gestational age.
Hint:
10
10
10
Σx-285 , Σ-8205, Σ)-78.4
=
i=1
10
10
= 627.88, Ex,y, = 2264.7
i-1
i-1
a. What is the best-fitting regression line relating mean thyroxine level to gestational age?
b. Is there a significant association between mean thyroxine level and gestational age?
Report a p-value.
Transcribed Image Text:4. Transient hypothyroxinemia, a common finding in premature infants, is not thought to have long- term consequences or to require treatment. A study was performed to investigate whether hypothyroxinemia in premature infants is a cause of subsequent motor and cognitive abnormalities [16]. Blood thyroxine values were obtained on routine screening in the first week of life from 536 infants who weighed 2000 g or less at birth and were born at 33 weeks gestation or earlier. The data in Table 11.21 were presented concerning the relationship between mean thyroxine level and gestational age. Hint: 10 10 10 Σx-285 , Σ-8205, Σ)-78.4 = i=1 10 10 = 627.88, Ex,y, = 2264.7 i-1 i-1 a. What is the best-fitting regression line relating mean thyroxine level to gestational age? b. Is there a significant association between mean thyroxine level and gestational age? Report a p-value.
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