I are studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that you postulate has 4 transmembrane segments. Explain why the sequence would lead to this hypothesis (what procedure would I have applied).

I are studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that you postulate has 4 transmembrane segments. Explain why the sequence would lead to this hypothesis (what procedure would I have applied).

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter19: Genomes And Proteomes

Section: Chapter Questions

Problem 1ITD: Below is a sequence of 540 bases from a genome. What information would you use to find the...

See similar textbooks

Related questions

Q: Vildtype pea plants have inflated pea pods and round seeds. Constricted pea pods and wrinkled seeds…

A: Alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: 1.) Draw and label a high-magnification of stratified squamous epithelium, including the basement…

A: Stratified squamous epithelium comprises numerous layers of flattened, scale-shaped cells. It…

Q: Porifera A. B. Cnidaria C. Echinodermata D. Deuterostomia E. V. Chordata F. G. N. Platyhelminthes H.…

A: These are term related to animal diversity.

Q: Give typed explanation Use the diagram representing the typical steps in gene expression and…

A: Gene expression occurs in four steps-In the first step, active portion of the DNA in the form of a…

Q: In order to estimate the number of flowering dogwoods in a 50 000 m² nature park, a researcher…

A: Q. 1 AnswerTo estimate the number of dogwoods in bloom in the entire 50,000 square meter nature…

Q: 5. Explain why a person with relative polycythemia would have a higher than normal red cell count…

A: Dehydration occurs when your body loses more fluids than it takes in, leading to symptoms like…

Q: 10. Based on the following phylogenetic tree, which of the following conclusions are "NOT correct?…

A: Phylogenetic tree is defined as the diagrammatic representation of evolutionary relationships among…

Q: estion 11 Match the correct letter with the correct statement. You may use a letter more than once A…

A: The image shows various atoms linked together by covalent and hydrogen bonds. In comparison to…

Q: Describe how the data are presented in the figure “0%”. Compare the presentation of data seen in…

A: This question involves the analysis and interpretation of data related to dog behavior and magnetic…

Q: Suppose researchers identified two Drosophila melanogaster mutant phenotypes. One phenotype is…

A: Answer :- To determine the mode of inheritance for the genes controlling maniac and shiny, we can…

Q: Drug XYZ has the following dosing guidelines: initiate therapy at 4-6mg/kg/day IV once daily for 2…

A: Patient's weight: 176 lbInitial dose: 5 mg/kg/dayStep 1: Convert the patient's weight from pounds…

Q: A portion of a gene is shown below. 5-ATGATTCGCCTCGGGGCTCCCCAGTCGCTGGTGCT-…

A: The part of the DNA that undergoes transcription is known as the gene. DNA is composed of two…

Q: A corn plant known to be heterozygous at three loci is testcrossed. The progeny phenotypes and…

A: Understanding the arrangement of genes on chromosomes and their linkage relationships is crucial in…

Q: If a father has Marfan syndrome, but the mother does not, and he passes the disease down to only…

A: Answer :- Marfan syndrome is a rare genetic disorder characterized by a variety of symptoms,…

Q: Send me 5 research articles releated to stem cell therapy in animals .

A: Stem cell therapy is introduction of new adult stem cells into damaged tissue in order to treat…

Q: Which statements describe Y-linked traits? At least 50% of the male and female offspring will…

A: Y-linked, also known as holandric inheritance (from Ancient Greek hólos meaning"whole" , andrós…

Q: G protein coupled receptors play an important role in signal transduction in many cells. Label the…

A: Cells in our body interact with each other through chemical molecules. Usually hormones, growth…

Q: Evolution takes place through a combination of mechanisms at the level of populations. This process…

A: Evolution is a steady phenomenon that brings about alterations in life forms from simple to more…

Q: Match the following: 5 2 cortisol insufficiency excess androgens excess cortisol excess…

A: Hormonal imbalance is an endocrine condition that occurs when the body produces too much or too low…

Q: Calculate the mitotic index for this cell sample. Scenics &Science/Alamy Stock Photo O 0/4 or 0% O…

A: 1- Mitotic index is the ratio of cells undergoing mitosis to the given number of cells.2- During…

Q: Please draw a monomer of DNA, label all parts and the carbon numbers on the sugar (as shown in…

A: The monomer, or building block, of DNA is the nucleotide. A nucleotide consists of three main…

Q: After an action potential is fired, the neuron returns to its resting state with the help of... 1.…

A: The sodium-potassium pump is a protein that uses energy from ATP to move sodium and potassium ions…

Q: t A: What is the frequency of the heterozygous genotype if the homozygous genotype frequencies are…

A: According to Hardy Weinburg's equation p2 + q2 + 2pq =1 and p + q =1Where, p = frequency of the…

Q: a) There are three distinct phases shown in the diagram (A, B, C). Describe what is happening to the…

A: What is population growth - Population growth is the increase in the number of individuals in a…

Q: Give an overview of the different characteristics of the major animal phyla using the table below

A: In the animal kingdom, a staggering diversity of life forms exists, each with unique characteristics…

Q: A. You cross a true-breeding sunflower, with yellow flowers and black seeds, with another…

A: True-breeding plants are those that consistently produce offspring with the same traits as the…

Q: [Na+] high K+] low [Na+] low [K+] high excess + charge excess - charge 3 Na+ 2 K | I ↑ 3 Nat 2 K+ 2…

A: An animal's cell, the plasma membrane has a transmembrane protein pump called the sodium-potassium…

Q: Draw the gel electrophoresis results for the following 16 kb plasmid when the plasmid is cut with…

A: DNA is composed of nitrogenous bases (A, T, G, C), deoxyribose sugar and a phosphate molecule.…

Q: Which of the following definitions are adequate as genus and differentia definitions and which are…

A: In the study of definitions and meaning, it’s crucial to understand the concept of genus and…

Q: Active transport requires peripheral proteins channel proteins transport proteins

A: The plasma/cell membrane acts as a barrier allowing the movement of only specific molecules inside…

Q: Rank from the first to the last steps to describe the correct order of events of glycolysis. Glucose…

A: Glycolysis is the first process of cellular respiration that occurs in both presence and absence of…

Q: Thats wrong. What would be the correct answer?

A: Alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: "One gene makes one RNA makes one protein". Is this true? Explain.

A: The "one gene makes one RNA makes one protein" dogma simplifies how genes are expressed. In general,…

Q: In Drosophila, raspberry eyes (ras) is a sex-linked trait (X chromosome) and recessive. Polished…

A: Suppose, the allele P (dominant) is wild type eyes and allele p (recessive) is responsible for…

Q: What are the predicted offspring genotype frequencies? A. TT: 25%, tt: 25%, Tt: 50% B. TT:…

A: In classical genetics, the idea of a monohybrid cross addresses the transmission of a single genetic…

Q: Match the cell structure with its function Golgi apparatus Lysosome Centriole Peroxisome Nucleolus…

A: Ans.The correct matches between cell structures and their functions are as follows:Mitochondria:…

Q: Stephanie conducts an experiment to study sex reversal in a specific grographic location. She…

A: Females are born with two X chromosomes. Female somatic cells are not involved in sexual…

Q: Identify the community interaction that best corresponds to the following example:" Lichens look…

A: A pack of wolves in a forest represents the population level of organization in an ecological…

Q: Body Weight: 58.5kg Height: 170cm Wrist Circumference: 15.2cm Height-Wrist…

A: The individual's health assessment based on the provided measurements generally indicates positive…

Q: The figure below illustrates the development of white blood cells from stem cells in the bone marrow…

A: White blood cells, or leukocytes, are vital components of the human immune system. They originate…

Q: 5. Lamarck's explanation of how species come to have different shapes, like tigers, snakes, humans,…

A: Evolution is the process by which the inherited traits of biological populations evolve through…

Q: Give typed explanation Which of the following is the correct order of events of coagulation? (1)…

A: The mechanism through which blood transforms from a fluid to a gel and forms a blood clot is…

Q: administer

A: Weight = 35lb ÷ 2.2 = 15.9 kg

Q: electrons electron distribution harm living organisms valence electrons charge distribution atoms…

A: These paragraphs talk about the basic structure of an element, how the molecules and atoms play an…

Q: Microscope parts Oculars/ Eyepiece Objective Lenses Objective Turret Light Source Diaphragm…

A: A microscope is a scientific tool used for magnifying and studying tiny objects or specimens. It…

Q: 2. Dosage compensation in mammals typically involves the random inactivation of one of the two X…

A: Black male (XbY): Can produce two types of gametes, Xb and Y."Calico" female (XBXb): Can produce two…

Q: Select the action for which the featured muscle is responsible. Depresses mandible Elevates tongue…

A: Muscular system is a part of body system which is involved in contraction and relaxation of muscles…

Q: There are 4 possible diploid genotypes at a locus with 2 alleles. O True False

A: Alleles at the alternative forms of a gene that are located at the same locus of a homologous…

Q: Which of the following statements are correct? Multiple choices can be correct.

A: The given statements are evaluated and explained which are correct and which are incorrect in step…

Q: Capstone ideas for veterinarians

A: Veterinary medicine is the branch of medicine that deals mainly with the prevention, diagnosis and…

Concept explainers

Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.

Question

I are studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that you postulate has 4 transmembrane segments.

Explain why the sequence would lead to this hypothesis (what procedure would I have applied).

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1: What is a transmembrane?

VIEW

Step 2: Experiments to test transmembrane hypothesis

VIEW

Solution

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

I am studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that you postulate has 4 transmembrane segments. What kind of experiment would allow me to test this hypothesis that there are 4 trans membrane segments?
As we focused on the genetic code and the transcription of genetic information stored in DNA into complementary RNA molecules. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: Question: How were the experimentally derived triplet codon assignments verified in studies using bacteriophage MS2?
As we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this informationwas acquired. From the explanations given in the chapter,what answers would you propose to the following fundamentalquestion What experimentally derived information led to Holley’sproposal of the two-dimensional cloverleaf model of tRNA?
Why does the sequence ITLIIFGVIAGVIGTILLI more likely to contain a membrane-spanning sequence?
As we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this informationwas acquired. From the explanations given in the chapter,what answers would you propose to the following fundamentalquestion What experimental information verifies that certain codonsin mRNA specify chain termination during translation?
Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human β-globin gene (Shown in Figure 17.11) into bacterial cells, hoping the cells will express it and synthesize functional β-globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does β-globin made by a eukaryotic cell. Explain why.
If you wanted to estimate the molecular weight of a newly isolated protein (no known amino acid sequence) as close to its actual molecular weight as possible, what technique might you use and please explain why.
Discuss why you think the ribosomes need to contain so many proteins and rRNA molecules. Does it seem like a waste of cellular energy to make such a large structure so that translation can occur?
The template strand of a double helical segment of DNA consists of the following sequence: 5’-GTAGCCTTAAGCGATCACCGTCCGTATTACTAGTGGCCAGACTCTTTTCACTCTCATGTATAGTTG-3’ Following translation process, what is the amino acid sequence that will be coded for? (show your answer using THREE-letter amino acid code starting from N-terminus to C-terminus)
Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human - globin gene (shown in the figure below (Links to an external site.)) into bacterial cells, hoping the cells will express it and synthesize functional - globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does -globin made by a eukaryotic cell. Explain why and give thoughts as to how to overcome this.
The template strand of a double helical segment of DNA consists of the following sequence: 5’-GTAGCCTTAAGCGATCACCGTCCGTATTACTAGTGGCCAGACTCTTTTCACTCTCATGTATAGTTG-3’ Following translation process, what is the amino acid sequence that will be coded for? (show your answer using ONE-letter amino acid code starting from N-terminus to C-terminus)
Although techniques are available for determining the sequences of amino acids in proteins, it is becoming more and more common to sequence proteins indirectly by determining the base sequence of the gene for the protein and then inferring the amino acid sequence from the genetic-code relationships. Suggest why the latter technique is being used for proteins.