Question 3Syed(producessperm)Anna(produceseggs)A| |BC| | || |D|| Question 3Anna (who produces eggs) and Syed (who produces sperm), have a child with Down's syndrome that results fromtrisomy of chromosome 21. Using a microsatellite sequence on chromosome 21, you run a gel. The gel imaged isattached; darker bands indicate signals of twice the intensity.If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of theirchild? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect.Assume no recombination.

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Description: Question 3Syed(producessperm)Anna(produceseggs)A| |BC| | || |D|| Question 3Anna (who produces eggs) and Syed (who produces sperm), have a child with Down's syndrome that results fromtrisomy of chromosome 21. Using a microsatellite sequence on chromo

Down syndrome is a congenital disorder that affects the child physically and mentally from his/her…

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If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of their child? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect. Assume no recombination.

If a nondisjunction event occurred in Anna during meiosis I, which lane (A, B, C, D) best fits the genotype of their child? Explain your choice, clearly identifying why that lane is correct and why the other lanes are incorrect. Assume no recombination.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter2: Cells And Cell Division

Section: Chapter Questions

Problem 25QP: We are following the progress of human chromosome 1 during meiosis. At the end of prophase I, how...

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A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement between the second andthird chromosomes. Her chromosomes, compared to those in anormal karyotype, are diagrammed on the next page:(a) What kind of chromosomal aberration is shown? (b) Using a drawing, demonstrate how these chromosomeswould pair during meiosis. Be sure to label the differentsegments of the chromosomes.(c) This woman is phenotypically normal. Does thissurprise you? Why or why not? Under what circumstancesmight you expect a phenotypic effect of such arearrangement? The woman in above problem has had two miscarriages. Shehas come to you, an established genetic counselor, with thesequestions:(a) If not, what is the chance that she could have a normalchild? Provide an informed response to her concerns
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