If a population has allele frequencies for A1 and A2 at 0.9 and 0.1 respectively, what is the probability that A2 is lost if the next generation has 12 offspring? What would be the probability if there were 100 offspring?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 2QP: How Can We Measure Allele Frequencies in Populations? The MN blood group is a single-gene,...
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If a population has allele frequencies for A1 and A2 at 0.9 and 0.1 respectively, what is the probability that A2 is lost if the next generation has 12 offspring? What would be the probability if there were 100 offspring?
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How do you get the probability of 81% for A2 being lost? And why do you multiply by 1/4? 

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