If the imaginary replacement of either of two protons forms enantiomers, then those protons are said to be enantiotopic. The NMR is not a chiral probe, and it cannot distinguish between enantiotopic protons. They are seen to be “equivalent by NMR.” Show that the two Hc protons in cyclobutanol are enantiotopic.
If the imaginary replacement of either of two protons forms enantiomers, then those protons are said to be enantiotopic. The NMR is not a chiral probe, and it cannot distinguish between enantiotopic protons. They are seen to be “equivalent by NMR.” Show that the two Hc protons in cyclobutanol are enantiotopic.
Chapter61: Friedel–crafts Acylation
Section: Chapter Questions
Problem 7Q
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If the imaginary replacement of either of two protons forms enantiomers, then those protons are said to be enantiotopic. The NMR is not a chiral probe, and it cannot distinguish between enantiotopic protons. They are seen to be “equivalent by NMR.” Show that the two Hc protons in cyclobutanol are enantiotopic.
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