(ii) Draw the product R, including a detailed reaction mechanism for the conjugate addition reaction between the 1,3-dicarbonyl P and the a,ß-unsaturated ketone Q. EtO P OEt Q OEt Et3N R (iv) Explain why conjugate addition is favoured over direct addition to Q in this case.

(ii) Draw the product R, including a detailed reaction mechanism for the conjugate addition reaction between the 1,3-dicarbonyl P and the a,ß-unsaturated ketone Q. EtO P OEt Q OEt Et3N R (iv) Explain why conjugate addition is favoured over direct addition to Q in this case.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter24: Amines And Heterocycles

Section24.9: Heterocyclic Amines

Problem 24P

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Concept explainers

Alkynes

Alkynes are organic compounds that contain at least one triple bond between carbon-carbon atoms. They are a series of unsaturated compounds with a general molecular formula, CnH2n-2.

Question

(ii) Draw the product R, including a detailed reaction mechanism for the conjugate addition
reaction between the 1,3-dicarbonyl P and the a,ß-unsaturated ketone Q.
Eto
P
OEt
+
Q
OEt
Et3N
R
(iv) Explain why conjugate addition is favoured over direct addition to Q in this case.

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