In 1984, Robert Gallo and Luc Montagnier independently identified what is known today as HIV (human immunodeficiency virus). Worldwide, 17 million people suffer from HIV, which is a virus that attacks human T lymphocytes. The T lymphocytes, a crucial part of the immune system, mature in the thymus. As a result of HIV, B cell lymphocytes also decrease in number . Most HIV patients die because of other diseases like tuberculosis and cancer. Once an infected individual's lymphocytes count reaches less than 200 per cubic millimeter of blood (normal is 500-1100 T cells/mm^ 3 ) , susceptibility to disease increases, and levels below 10 can be fatal. A) How would a decrease in the thymus T cell lymphocytes cause an increase in susceptibility of disease? B) Identify the 4 types of Tlymphocytes that mature in the thymus, including their role in the immune response: C) A decrease in B cell lymphocytes would affect the immune system in what way ?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter17: Genes And The Immune System
Section: Chapter Questions
Problem 3QP: The Adaptive Immune Response Is a Specific Defense Against Infection Name the class of molecules...
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Use to answer: In 1984, Robert Gallo and Luc Montagnier independently identified what is known today as HIV (human immunodeficiency virus). Worldwide, 17 million people suffer from HIV, which is a virus that attacks human T lymphocytes. The T lymphocytes, a crucial part of the immune system, mature in the thymus. As a result of HIV, B cell lymphocytes also decrease in number . Most HIV patients die because of other diseases like tuberculosis and cancer. Once an infected individual's lymphocytes count reaches less than 200 per cubic millimeter of blood (normal is 500-1100 T cells/mm^ 3 ) , susceptibility to disease increases, and levels below 10 can be fatal. A) How would a decrease in the thymus T cell lymphocytes cause an increase in susceptibility of disease? B) Identify the 4 types of Tlymphocytes that mature in the thymus, including their role in the immune response: C) A decrease in B cell lymphocytes would affect the immune system in what way ?
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