In a mouse mutant, all Norepinephrine (NE) synapses in the thalamus have a ProteinKinase A that cannot be activated by cAMP. Which of the following effects wouldoccur? Check all correct answers.NE would not have target actions in thalamusProtein kinase A in the synapse could not phosphorylate its targetsAdenyl Cyclase would not functionCAMP could not be broken downthe alpha receptor coupled pathway would still function

Ans : Protein kinases belongs to the family of enzymes that phosphorylates the target protein by…

Answered: In a mouse mutant, all Norepinephrine…

In a mouse mutant, all Norepinephrine (NE) synapses in the thalamus have a Protein Kinase A that cannot be activated by CAMP. Which of the following effects would occur? Check all correct answers.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 2SQE

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Concept explainers

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.

Question

In a mouse mutant, all Norepinephrine (NE) synapses in the thalamus have a Protein
Kinase A that cannot be activated by cAMP. Which of the following effects would
occur? Check all correct answers.
NE would not have target actions in thalamus
Protein kinase A in the synapse could not phosphorylate its targets
Adenyl Cyclase would not function
CAMP could not be broken down
the alpha receptor coupled pathway would still function

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