close solutoin list

You learned in this chapter that Na + /K + active transport pumps in the plasma membrane of the axons are responsible for creating the imbalance between Na + and K + inside and outside of the neuron that produces the resting membrane potential. In early research studying the role of ions and the involvement of active transport of ions in neural signaling, investigators used the giant axon of a squid as a model. The diameter of a giant axon is far greater than that of a mammalian axon, which enabled researchers to isolate it easily and use it in in vitro experiments. In one early experiment, researchers investigated the active transport of Na + out of the axon in response to the presence of cyanide. Experimentally they hooked up a section of axon to a syringe, immersed the axon in artificial seawater, introduced radioactive 22 Na (as 22 NaCl) into the axon, and then quantified the transport of 22 Na out through the axon’s plasma membrane. The rate of 22 Na transport out of the axon was determined by measuring the radioactivity released into the fluid sur- rounding the axon over a period of time. The Figure shows the results of the experiment. What is the effect of cyanide on Na1 transport out of the squid axon? How do the data show the effect? Source: P. C. Caldwell et al. 1960. The effects of injecting “energy-rich” phosphate compounds on the active transport of ions in the giant axons of Loligo. The Journal of Physiology 152:561–590. © Cengage Learning 2017

BuyFind

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
Publisher: Cengage Learning
ISBN: 9781305389892
BuyFind

Biology: The Dynamic Science (Mind...

4th Edition
Peter J. Russell + 2 others
Publisher: Cengage Learning
ISBN: 9781305389892

Solutions

Chapter
Section
Chapter 39, Problem 1ITD
Textbook Problem

You learned in this chapter that Na+/K+ active transport pumps in the plasma membrane of the axons are responsible for creating the imbalance between Na+ and K+ inside and outside of the neuron that produces the resting membrane potential. In early research studying the role of ions and the involvement of active transport of ions in neural signaling, investigators used the giant axon of a squid as a model. The diameter of a giant axon is far greater than that of a mammalian axon, which enabled researchers to isolate it easily and use it in in vitro experiments. In one early experiment, researchers investigated the active transport of Na+ out of the axon in response to the presence of cyanide. Experimentally they hooked up a section of axon to a syringe, immersed the axon in artificial seawater, introduced radioactive 22Na (as 22NaCl) into the axon, and then quantified the transport of 22Na out through the axon’s plasma membrane. The rate of 22Na transport out of the axon was determined by measuring the radioactivity released into the fluid sur- rounding the axon over a period of time. The Figure shows the results of the experiment.

Chapter 39, Problem 1ITD, You learned in this chapter that Na+/K+ active transport pumps in the plasma membrane of the axons

What is the effect of cyanide on Na1 transport out of the squid axon? How do the data show the effect?

Source: P. C. Caldwell et al. 1960. The effects of injecting “energy-rich” phosphate compounds on the active transport of ions in the giant axons of Loligo. The Journal of Physiology 152:561–590.

© Cengage Learning 2017

Expert Solution

Want to see this answer and more?

Experts are waiting 24/7 to provide step-by-step solutions in as fast as 30 minutes!*

See Solution

*Response times vary by subject and question complexity. Median response time is 34 minutes and may be longer for new subjects.

Chapter 39 Solutions

Biology: The Dynamic Science (MindTap Course List)
Show all chapter solutions

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions
What percentage of its food supply does the United States waste each year a. 20 percent b. 30 percent c. 40 per...

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

A 65.0-kg boy and his 40.0-kg sister, both wearing roller blades, face each other at rest. The girl pushes the ...

Physics for Scientists and Engineers, Technology Update (No access codes included)

What happens to airflow between circulation cells? (Hint: What causes Earths desert climates?)

Oceanography: An Invitation To Marine Science, Loose-leaf Versin