In a tabular form; identify biochemical reactions and the enzymes in each step in the urea cycle.
Q: Illustrate the urea cycle. Briefly explain the process.
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Q: The TCA cycle intersects with the urea cycle via the malate-aspartate shuttle. A) True B) False
A: false the TCA cycle interacts with the urea cycle via the glutamate- aspartate shuttle.
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Q: The usual keto acid involved for transamination reaction is succinate.
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- hyperammonemia in patients is compounded by the reality of the normal regulatory controls in the urea cycle. Explain how increased GDH oxidative deamination activity will inhibit the urea cycle.Whatis the purpose of the urea cycle? Include a net reaction for the urea cycle.In order to function as a coenzyme, a derivative of pyridoxine (Vit. B6) is necessary. a.transamination b.Deamination by oxidation c. transamination as well as oxidative deamination are involved. d.The urea cycle is the fourth step.
- Which of the following statements regarding the urea cycle is true? (A) Fumarate acts as a connecting link between urea cycle and the CAC.(B) The urea cycle occurs solely in the mitochondria.(C) Citrulline and arginine reacts to form argininosuccinate.(D) Ornithine formed in the last reaction of the urea cycle is excreted from the body along with urea.(E) The purpose of the urea cycle is to produce energy (4 ATP per ammonia that enters) for the liver.18. What key molecule connects the urea cycle with the TCA cycle? A. Fumarate B. Malate C. Arginine D. Arigininosuccinate E. Aspartate 19. What meal would increase the activity/need for urea cycle enzymes? A. Steak and a milkshake B. Spinach salad and diet coke C. PB&J sandwich and glass of water D. Curly fries and a lemonade 20. What is the allosteric activator of carbamoyl phosphate synthetase I? A. Glutamate B. N-acetylglutamate C. Bicarbonate D. Urea as a feedback negative regulator E. ArginineThe committed step in the urea cycle is: A、condensation of citrulline with aspartate B、export of citrulline from the matrix C、cleavage of urea from arginine D、Formation of carbamoyl phosphate
- The function of …………………………………… in the urea cycle is similar to the function of oxaloacetate in TCA cycle.Define the following terms: a. ketogenic amino acid b. glucogenic amino acid c. L-amino acid oxidase d. Krebs urea cycle e. CPSIDiscuss the toxic effects of the ammonium ion and excess bicarbonate ion. What is the effect of high concentrations of NH4+ in the bloodstream? What are the two reasons NH4+ is so toxic to the brain? Why can the urea cycle also be considered as a bicarbonate ion disposal mechanism? Why is that important?
- Consider the following Statements: (1) Citric acid cycle intermediates are often the products from amino acid carbon skeleton degradation. (2) The net effect of transamination is to collect the amino groups from a variety of amino acids into the amino acids glutamate and aspartate. (3) All of the reactions of the urea cycle occur within mitochondria. how many is trueWhich of the following statements is/are TRUE for the urea cycle? It has a direct link with the TCA cycle. It has a direct link with the β-oxidation cycle It is an amphibolic process of N. It occurs in the mitochondria and cytosol of liver.Discuss the two roles of N-acetylglutamate in the urea cycle. Include relevant chemical structures and reactions. What is the regulatory function of N-acetylglutamate in the urea cycle? What is the other role of N-acetylglutamate in relationship to the urea cycle? Glutamate is the precursor for N-acetylglutamate. How is glutamate involved in the connection between the urea cycle and the CAC?