In patient with Citrullinemia, citrulline is accumulated in both the blood and urine. Using your knowledge of the reactions of urea cycle explain the accumulation of citrulline described.
Q: Illustrate the urea cycle. Briefly explain the process.
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Q: NH4 Water+ Carbon Dioxide + ATP A F B THE UREA CYCLE D
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Q: Which compounds link the urea and Krebs cycles?
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Q: Which of the information given about urea synthesis is not true? It takes place for the…
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Q: Fumarate produced during urea cycle operation is processed further via
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Q: The major site of urea synthesis i
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Q: (c) Describe the reversible steps in the urea cycle, including the substrates, products, and…
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Q: Discuss the toxic effects of the ammonium ion and excess bicarbonate ion. What is the effect of…
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Q: Explain why one might provide high concentrations of the amino acid Arg to patients who have a…
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Q: Identify the INCORRECT statement concerning the urea cycle. Ureas is the compound used by some…
A: Introduction Urea is formed from ammonia, CO2 , and aspartate following a cyclical pathway, known as…
Q: By definition, essential amino acids are not synthesized by an organism. Arginine is classified as…
A: Amino acids are the building blocks of amino acids which are broadly classified into two types based…
Q: Why can’t humans simply excrete waste nitrogen atoms asammonia rather than utilize the energetically…
A: Protein degradation produces ammonia. The nitrogenous waste differs in different organisms. Most of…
Q: Production of the enzymes that catalyze the reactions of the urea cycle can increase or decrease…
A: The removal of toxic and harmful substances from the body, like ammonia, occurs through the urea…
Q: The urea cycle occurs partially in the cytosol and partially in the mitochondria. Discuss the urea…
A: The urea cycle is the metabolic process that allows the excretion of ammonia by transferring the…
Q: Mammals excrete most nitrogen atoms as urea. The urea cycle itself requires considerable amounts of…
A: The urea cycle is used for the conversion of toxic substances from amino acid metabolism ammonium…
Q: Write out the series of reactions that are involved in the urea cycle in mammals and amphibians.…
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Q: How does the level of glutamic acid affect the urea cycle?
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Q: The urea cycle occurs partially in the cytoplasm andpartially in the mitochondria. Discuss the urea…
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A: The cycle involving biochemical reactions for the production of urea from ammonia is referred to as…
Q: The first two steps involved in the urea cycle occurs in the mitochondria while the remaining steps…
A: Asked : The statement given is correct or incorrect
Q: Using the model above, illustrate the urea cycle.
A: Ammonium ions are released during the metabolism of proteins. These ammonium ions are converted into…
Q: Briefly discuss why part of urea cycle takes place in mitochondria.
A: Living organisms excrete the excess nitrogen resulting from the metabolic breakdown of amino acids…
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Q: Explain the importance of the urea cycle in the body.
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Q: In the urea cycle, urea is synthesized from carbon dioxide and____________________.
A: The urea cycle is also known as the ornithine cycle, It is a cycle of biochemical reactions that…
Q: All defects in the urea cycle lead to an elevated level of ammonium ion in blood, which is called:…
A: Urea cycle is a metabolic pathway,which is involved in the removal of nitrogenous wastes from the…
Q: hyperammonemia in patients is compounded by the reality of the normal regulatory controls in the…
A: The process of the oxidative deamination converts the amino acid glutamate to the metabolite alpha…
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Q: All are enzymes involved in the urea cycle except . A. Carbamoyl phosphate synthase -II B. Ornithine…
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- Discuss the toxic effects of the ammonium ion and excess bicarbonate ion. What is the effect of high concentrations of NH4+ in the bloodstream? What are the two reasons NH4+ is so toxic to the brain? Why can the urea cycle also be considered as a bicarbonate ion disposal mechanism? Why is that important?hyperammonemia in patients is compounded by the reality of the normal regulatory controls in the urea cycle. Explain how increased GDH oxidative deamination activity will inhibit the urea cycle.All defects in the urea cycle lead to an elevated level of ammonium ion in blood, which is called: hyperammonemia. hypoammonemia. toxaemia. ammonemia. anemia.
- The urea cycle occurs partially in the cytoplasm andpartially in the mitochondria. Discuss the urea cyclereactions with reference to their cellular locations.The urea cycle has no known off switch. Why does that make physiological sense?Explain why the symptoms of a partial defi ciency in a urea cycle enzyme can be attenuated by a low-protein diet.
- The enzyme carbamoyl phosphate synthetase is activated when the glutamate concentration decreases, which in turn activates the urea cycle. True Or FalseUrea is a metabolic by-product of the catabolism of _____________.Citrullene is a special amino acid that is used in the urea cycle and as a precursor for synthesis of the aminoacid Arg in the body. In which category would you place citrullene? Explain.