In most two-factor crosses involving linked genes, we cannot tellif a double crossover between the two genes has occurred becausethe offspring will inherit the nonrecombinant pattern of alleles.How does the inability to detect double crossovers affect thecalculation of map distance? Is map distance underestimated oroverestimated because of our inability to detect double crossovers?Explain your answer.
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
In most two-factor crosses involving linked genes, we cannot tell
if a double crossover between the two genes has occurred because
the offspring will inherit the nonrecombinant pattern of alleles.
How does the inability to detect double crossovers affect the
calculation of map distance? Is map distance underestimated or
overestimated because of our inability to detect double crossovers?
Explain your answer.
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