In the Ca++ current traces below, why is the current different during the test condition? +20 mV Ем -40 mV IM Control TEST

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter18: Iv Flow Rate Calculation
Section: Chapter Questions
Problem 2.3P
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In the Ca++ current traces below, why is the current different during the test condition?
+20 mV
Ем
-40 mV
IM
Control
TEST
Transcribed Image Text:In the Ca++ current traces below, why is the current different during the test condition? +20 mV Ем -40 mV IM Control TEST
TEST
Intracellular Ca++ concentration is increased
EGTA is added to the inside of the cell
Extracellular Ca++ is replaced with Cl-
Ca++ channels activate slower
Transcribed Image Text:TEST Intracellular Ca++ concentration is increased EGTA is added to the inside of the cell Extracellular Ca++ is replaced with Cl- Ca++ channels activate slower
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