In the presence of probenecid, the filtration rate of penicillin is significantly reduced, leading to lower clearance rates for penicillin and a sustained therapeutic effect.  True  False 2.  Substances that are actively secreted into the tubular lumen may have clearance rates that exceed GFR.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter14: The Urinary System
Section14.2: Glomerular Filtration
Problem 2CYU
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  1. In the presence of probenecid, the filtration rate of penicillin is significantly reduced, leading to lower clearance rates for penicillin and a sustained therapeutic effect.

     True

     False

    2. 

    1. Substances that are actively secreted into the tubular lumen may have clearance rates that exceed GFR.

       True

       False

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