Is a step-wise approach, such as that outlined below, needed to accomplish this aldol reaction? Why? LDA CH;CH2CHO ОН O a) Yes, to ensure proper enolate formation and limit product mixtures O b) Yes, to ensure proper enolate formation as the only reason O c) Yes, to limit product mixtures only O d) No, this reaction would work well under one-pot conditions with NaOH (aq)

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter18: Ethers And Epoxides; Thiols And Sulfides
Section18.SE: Something Extra
Problem 69GP
icon
Related questions
Question
Is a step-wise approach, such as that outlined below, needed to accomplish this aldol
reaction? Why?
LDA
CH;CH2CHO
ОН
O a) Yes, to ensure proper enolate formation and limit product mixtures
O b) Yes, to ensure proper enolate formation as the only reason
O c) Yes, to limit product mixtures only
O d) No, this reaction would work well under one-pot conditions with NaOH (aq)
Transcribed Image Text:Is a step-wise approach, such as that outlined below, needed to accomplish this aldol reaction? Why? LDA CH;CH2CHO ОН O a) Yes, to ensure proper enolate formation and limit product mixtures O b) Yes, to ensure proper enolate formation as the only reason O c) Yes, to limit product mixtures only O d) No, this reaction would work well under one-pot conditions with NaOH (aq)
What statement best describes the next step in the aqueous basic catalyzed aldol
condensation of propanal?
a) Proton transfer from water to oxyanion
b) Elimination of water
O C) Proton transfer from NaOH to oxyanion
O d) Addition of water
Transcribed Image Text:What statement best describes the next step in the aqueous basic catalyzed aldol condensation of propanal? a) Proton transfer from water to oxyanion b) Elimination of water O C) Proton transfer from NaOH to oxyanion O d) Addition of water
Expert Solution
steps

Step by step

Solved in 3 steps with 2 images

Blurred answer
Knowledge Booster
Protection of Groups in Organic Synthesis
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9781305080485
Author:
John E. McMurry
Publisher:
Cengage Learning