The Stork reaction is a condensation reaction between an enamine donor and an a,ß-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,ß-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between cyclohexanone and propenal. (1 Draw the structure of the product of the enamine formed between cyclohexanone and morpholine. C P opy aste ChemDoodle Submit

Organic Chemistry: A Guided Inquiry
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Chapter25: Enolate & Enol Nucleophiles
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The Stork reaction is a condensation reaction between an enamine donor and an α,β-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of

  1. formation of an enamine from a ketone,
  2. Michael addition to an α,β-unsaturated carbonyl compound, and
  3. hydrolysis of the enamine in dilute acid to regenerate the ketone.

Consider the Stork reaction between cyclohexanone and propenal.

This question has multiple parts. Work all the parts to get the most points.
The Stork reaction is a condensation reaction between an enamine donor and an a,6-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of
1. formation of an enamine from a ketone,
2. Michael addition to an a,ß-unsaturated carbonyl compound, and
3. hydrolysis of the enamine in dilute acid to regenerate the ketone.
Consider the Stork reaction between cyclohexanone and propenal.
Draw the structure of the product of the enamine formed between cyclohexanone and morpholine.
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Transcribed Image Text:This question has multiple parts. Work all the parts to get the most points. The Stork reaction is a condensation reaction between an enamine donor and an a,6-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,ß-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between cyclohexanone and propenal. Draw the structure of the product of the enamine formed between cyclohexanone and morpholine. P aste ChemDoodle Submit
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