is NH2 stays pronated at pH 1 for Proline in this amino acids chain??? what would be the NH2's charge of proline??? since my professor said that proline does not have a ionizable side chain, so would it be NH2 or NH2+ for a given amino acid At pH1, is it NH2-Pro-Leu-COOH??? or NH3-Pro-Leu-COOH?????

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter22: Proteins
Section: Chapter Questions
Problem 22.61P: 22-61 Polyglutamic acid (a polypeptide chain made only of glutamic acid residues) has an a-helix...
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is NH2 stays pronated at pH 1 for Proline in this amino acids chain??? what would be the NH2's charge of proline??? since my professor said that proline does not have a ionizable side chain, so would it be NH2 or NH2+ for a given amino acid

At pH1, is it NH2-Pro-Leu-COOH??? or NH3-Pro-Leu-COOH?????

ffe
H₂N-Cys-Lys-Asp -Asp -Glu-Pro-Leu - Ary-Lys-Glu-call
12.48 10.53 4.25 2.91
10.78 €60 8.33 10.53 3.86 3.86 4.25
(3)
NH₂ Cys Lys Asp Asp Glu Pro Lew Ary Lys Ghu Coon charge
PH110
0 0 0 +1 +1
+10
O
O
O
+
34
PH 7 +1
+1 -1
-1-10
+1 +1
PH14
O
O
| PH= 1
PH= 17
PH=14
1
0|-||-1|-1|0
O O
B charge of
在中间ASH和COOH (失去活性)
Leu Cool Charge
NH2 Pro
-1 - 1
04
-on 0=0
HO
i-on
ج-E
-N-C-C-N
anide
group
R
-1
+
-6
4
carboxyl
днир
combined
peptule bord.
Transcribed Image Text:ffe H₂N-Cys-Lys-Asp -Asp -Glu-Pro-Leu - Ary-Lys-Glu-call 12.48 10.53 4.25 2.91 10.78 €60 8.33 10.53 3.86 3.86 4.25 (3) NH₂ Cys Lys Asp Asp Glu Pro Lew Ary Lys Ghu Coon charge PH110 0 0 0 +1 +1 +10 O O O + 34 PH 7 +1 +1 -1 -1-10 +1 +1 PH14 O O | PH= 1 PH= 17 PH=14 1 0|-||-1|-1|0 O O B charge of 在中间ASH和COOH (失去活性) Leu Cool Charge NH2 Pro -1 - 1 04 -on 0=0 HO i-on ج-E -N-C-C-N anide group R -1 + -6 4 carboxyl днир combined peptule bord.
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