It is clear that patterns of genetic variation among populations can affect both disease risk and treatment efficacy and safety. Yet, a majority of studies still occur in European ancestry populations and the results can have limited utility across populations. Do you have any suggestions or plans to solve these problems

It is clear that patterns of genetic variation among populations can affect both disease risk and treatment efficacy and safety. Yet, a majority of studies still occur in European ancestry populations and the results can have limited utility across populations. Do you have any suggestions or plans to solve these problems

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter14: Biotechnology And Society

Section: Chapter Questions

Problem 10QP

See similar textbooks

Similar questions

Do you think there is a need to validate problem prioritization? Why or why not? Why do you think there is a need to collect data in problem identification?
In a group of patients, it is reported that drug p is effective only in individuals of the recessive phenotype. if q = .6 and p to .4 what fraction of patients would benefit from the treatment. Assume that the population is in HW equilibrium? a. .25 b. .36 c. .4 d. .6
The population risk of NIDDM is highly dependent on the population under consideration; in most populations, this risk is 1%-5%, although it is 6% to 7% in the United States. If a patient has one affected sibling, the risk increases to 10%; an affected sibling and another first-degree relative, the risk is 20%; an affected monozygotic twin, the risk is 50%-100%. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.
How would you respond to someone who said that models are useless in studying population genetics because they represent oversimplifications of the real world?
Please help with the following: How does penetrance differ from expressivity in genetics? A. Penetrance is the percentage of individuals with a specific genotype that exhibit the expected phenotype while expressivity is the degree to which a phenotypic character is expressed. B. Penetrance is the degree of lethality of a specific genotype while expressivity is how frequently that genotype is seen in the population. C. Penetrance is the presence of more than two alleles at a locus within a group of individuals while expressivity is the influence of sex on which alleles express themselves. D. None of the above. E. Penetrance refers to the paternal effects of a gene while expressivity refers to the maternal effects of a gene.
What are the different genetic markers that genome-wide association studies (GWAS) employ? How can scientists use this data to calculate the disease risk associated with each variation?
How might the Hardy Weinberg relationship be used to evaluate a new SNP genotyping technology using multiple individuals from a population? Group of answer choices a)If genotypes match the reference genome, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs. b)If observed phenotypes follow Hardy Weinberg, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs. c)If genotypes and allele frequencies follow Hardy Weinberg, the technology is sound. Otherwise, the technology may have problems accurately calling SNPs. d)None of the above
Why do you think a genetic bottleneck is more likely to occur in a small population than in a large population?
subset of African diversity can be found in the genomes of all populations existing today. a. A subset of African diversity can only be found in populations whose ancestors migrated out of Africa at any point in time. b. African diversity is only found in the genomes of population with direct ancestors from Africa migrating from the continent in the last 160KY. c. True statement d. False statement Please answer asap and type your answer and do not copy from anywhere please
How do I find the frequency of alleles in this population? Please explain how to solve this problem.
While studying the frequency of sickle-cell disease ("sickle cell anemia") in a population living in sub-Saharan Africa, you obtain the following data from a sample of n= 100 people (note that I chose a simpler system for identifying the alleles rather than using "Hb S" for sickle cell allele), which is the actual name and what you used in lab). What is the frequency of the sickle cell allele (b) in the sample below from a human population? Sample Data BB-60 individuals (No sickle cell disease) Bb-30 individuals (No sickle cell disease) bb-10 individuals (Sickle cell disease) 1. 0.25 2. 0.10 3. 0.35 4. 0.60 5. 0.20
Population bottlenecks are evident today in Arab communities, Israel, India, Thailand, Scandinavia, some African nations, and especially among indigenous peoples such as Native Americans. Research an indigenous or isolated population and describe a genetic condition that its members have that is rare among other groups of people, and how the population bottleneck occurred.