L.CH,M B дет дета НО (CH₂)₂N Compound A (CH₂) N Tamoxifen

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 63AP: As far back as the 16th century, South American Incas chewed the leaves of the coca bush,...
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17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the structure of compound A in the synthesis of tamoxifen. Page 707 HO (CH3)2N 1. C,H,MgBr 2. H + Compound A (CH3)2N Tamoxifen

17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the Page 707
structure of compound A in the synthesis of tamoxifen
НО
(CH₂)₂N
ge--ge
1.CH,MgBr
2. H,0
Compound A
(CH₂) N
Tamoxifen
Transcribed Image Text:17.36 Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the Page 707 structure of compound A in the synthesis of tamoxifen НО (CH₂)₂N ge--ge 1.CH,MgBr 2. H,0 Compound A (CH₂) N Tamoxifen
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