Lipid rafts are microdomains in the plasma membrane that function as a stable platform for signaling and trafficking. Which of the following helps make the lipid rafts more stable and less mobile? phospholipid cholesterol sphingolipid a and b b and c
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Lipid rafts are microdomains in the plasma membrane that function as a stable platform for signaling and trafficking. Which of the following helps make the lipid rafts more stable and less mobile?
- phospholipid
- cholesterol
- sphingolipid
- a and b
- b and c
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- The tails of the phospholipids of the plasma membrane are composed of _____ and are _____? a. phosphate groups; hydrophobic b. fatty acid groups; hydrophilic c. phosphate groups; hydrophilic d. fatty acid groups; hydrophobicA transmembrane protein has the following properties: it has two binding sites, one for solute A and one for solute b. The protein can undergo a conformational change to switch between two states: either both binding sites are exposed exclusively on one side of the membrane or both binding sites are exposed exclusively on the other side of the membrane. The protein can switch between the two conformational states only if both binding sites are occupied or if both binding sites are empty, but cannot switch if only one binding site is occupied. Do you need to specify any additional properties to turn this protein into a symport that couples the movement of solute A up its concentration gradient to the movement of solute b down its electrochemical gradient?A transmembrane protein has the following properties: it has two binding sites, one for solute A and one for solute b. The protein can undergo a conformational change to switch between two states: either both binding sites are exposed exclusively on one side of the membrane or both binding sites are exposed exclusively on the other side of the membrane. The protein can switch between the two conformational states only if both binding sites are occupied or if both binding sites are empty, but cannot switch if only one binding site is occupied. What kind of protein do these properties define?
- For a protein to be an integral membrane protein, it would have to be amphipathic, which means that it ________. has only hydrophilic regions has only hydrophobic regions has both hydrophilic and hydrophobic regions exposed on only one surface of the membraneBesides lipid molecules, cell membranes also contain many different types of proteins, each with specific functions. In the following table, select the common type of membrane protein in the right-hand column that each statement in the left-hand column describes. The choices on the Type of Membrane Protein are the same for theFunction of the Membrane ProteinWhich of the following is most likely NOT a function of Peripheral Proteins? support for membranes enzymes anchor for integral membrane proteins receptors
- "Although membrane domains with different protein compositions are well known, there are at present no examples of membrane domains that differ in lipid composition", is true or false.What would happen in each of the following cases where something related to intracellular transport is altered? Assume in each case that the protein involved is a soluble protein, not a membrane protein. State where each protein would be located and explain each of your answers. You add a signal sequence (for the Golgi) to the N-terminal end of a normally cytosolic protein. You change the hydrophobic amino acids in an ER signal sequence into other, hydrophobic, amino acids.What is the correct order of permeability for the following four substances across a pure phosopholipid bilayer? Ca+ > ATP > O2 > ethanol K+ > ethanol > CO2 > ATP CO2 > ethanol > K+ > GTP O2 > Ca+ > GTP > ethanol
- Which of these structures would you expect to find as part of the transmembrane portion of an integral membrane protein? Structure B would be part of the transmembrane domain of an integral membrane protein. Structure C would be part of the transmembrane domain of an integral membrane protein. Structure A would be part of the transmembrane domain of an integral membrane protein.What would happen in each of the following cases where something related to intracellular transport is altered? Assume in each case that the protein involved is a soluble protein, not a membrane protein. State where each protein would be located and explain each of your answers. You change the hydrophobic amino acids in an ER signal sequence into negatively charged amino acids. You discover a protein that has both an ER signal sequence and a nuclear localization sequence. The ER signal sequence is at the N-terminus of the protein, and the nuclear localization sequence is located in the middle of the protein.In the "fluid " _______ cell membrane model, lipids are organized in a ________ arrangement, such that _______ portions of the lipids are exposed to either the interior or exterior of the cell, while the lipid portions are sandwiched in the middle of the membrane. As part of the cell membrane, a main function of peripheral proteins is to provide _________ , while a main function of proteins is to provide _________ . Other cell membrane molecules include a compound called __________, which functions to provide fluidity to rigid membranes and rigidity to fluid membranes; and surface carbohydrates, which function in the membrane not to provide energy, but instead to provide _________ _____ . Aminophospholipids (including PE and ) move to the inner leaflet of the membrane, by an enzyme known as the ._______ A main function of the cell membrane is to be very selective as to what is able to cross through, a condition known as a barrier.
