Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD 50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD 50 value for FD&C Red Dye No. 40 is 10,000 mg/kg in rats. Assume that the LD 50 value for humans is the same as for rats. Calculate the number of number of glasses of Allura Red sports drink, each containing 8.8 mg of Allura Red, required to reach the LD 50 of 10,000 mg of Allura Red/kg body weight. Assume the person has a body weight of 165 lbs. 2.205 lbs 1 kg You may assume two significant figures but do not use sčientific notation. Do not include units with your answer.

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
Publisher:Skoog
Chapter7: Statistical Data Treatment And Evaluation
Section: Chapter Questions
Problem 7.19QAP
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Many common materials that we ingest, though quite safe in reasonable quantities,
become toxic when taken in very large doses. A measure of toxicity is the LD 50
value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material
per kg of subject-body-weight that, if administered to a population of subjects,
would cause 50% of the population to die. The LD 50 value for FD&C Red Dye No.
40 is >10,000 mg/kg in rats. Assume that the LD 50 value for humans is the same as
for rats.
Calculate the number of number of glasses of Allura Red sports drink, each
containing 8.8 mg of Allura Red, required to reach the LD 50 of 10,000 mg of Allura
Red/kg body weight. Assume the person has a body weight of 165 lbs.
2.205 lbs 1 kg
!!
You may assume two significant figures but do not use sčientific notation.
Do not include units with your answer.
Your Answer:
Answer
Transcribed Image Text:Many common materials that we ingest, though quite safe in reasonable quantities, become toxic when taken in very large doses. A measure of toxicity is the LD 50 value (Lethal Dose, 50%). It is the quantity of material, expressed in mg of material per kg of subject-body-weight that, if administered to a population of subjects, would cause 50% of the population to die. The LD 50 value for FD&C Red Dye No. 40 is >10,000 mg/kg in rats. Assume that the LD 50 value for humans is the same as for rats. Calculate the number of number of glasses of Allura Red sports drink, each containing 8.8 mg of Allura Red, required to reach the LD 50 of 10,000 mg of Allura Red/kg body weight. Assume the person has a body weight of 165 lbs. 2.205 lbs 1 kg !! You may assume two significant figures but do not use sčientific notation. Do not include units with your answer. Your Answer: Answer
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