Methionine can react with ATP to generate S-adenylmethionine (SAM). NH2 N но. NH2 но-р-о-р-о-р-о он Он но NN OH OH methionine АТР step 1 NH2 NH2 + HO. %3D + но-р-о-р-о-р-он Он OH OH но N. Он SAM triphosphate step 2 NH2 но. NH2 + но-Р-о-Р-он + но-р-он ÓH OH OH но OH N он pyrophosphate orthophosphate (D) Draw methionine in all lone pair electrons and indicate the hybridization for each carbon, oxygen, and nitrogen. (E) Step 1 at SAM synthesis proceeds by an SN2 mechanism. Draw the reaction mechanism using the arrow formalism. (F) Justify why this reaction proceeds via SN2 rather than SN1 mechanism.

Methionine can react with ATP to generate S-adenylmethionine (SAM). NH2 N но. NH2 но-р-о-р-о-р-о он Он но NN OH OH methionine АТР step 1 NH2 NH2 + HO. %3D + но-р-о-р-о-р-он Он OH OH но N. Он SAM triphosphate step 2 NH2 но. NH2 + но-Р-о-Р-он + но-р-он ÓH OH OH но OH N он pyrophosphate orthophosphate (D) Draw methionine in all lone pair electrons and indicate the hybridization for each carbon, oxygen, and nitrogen. (E) Step 1 at SAM synthesis proceeds by an SN2 mechanism. Draw the reaction mechanism using the arrow formalism. (F) Justify why this reaction proceeds via SN2 rather than SN1 mechanism.

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter29: The Organic Chemistry Of Metabolic Pathways

Section29.SE: Something Extra

Problem 24MP: One of the steps in the pentose phosphate pathway for glucose catabolism is the reaction of xylulose...

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