methyltransferase (TPMT) levels is correct? 27. In the context of 6-mercaptopurine (6-MP) therapy for leukemia, which statement about thiopurine A) High TPMT levels are associated with increased sensitivity to 6-MP and higher risk of adverse reactions. B) Low TPMT levels are associated with increased sensitivity to 6-MP and higher risk of adverse reactions decreased therapeutic efficacy C) High TPMT levels result in reduced metabolism of 6-MP, leading to D) Low TPMT levels result in increased metabolism of 6-MP, leading to excessive drug accumulation and toxicity.

methyltransferase (TPMT) levels is correct? 27. In the context of 6-mercaptopurine (6-MP) therapy for leukemia, which statement about thiopurine A) High TPMT levels are associated with increased sensitivity to 6-MP and higher risk of adverse reactions. B) Low TPMT levels are associated with increased sensitivity to 6-MP and higher risk of adverse reactions decreased therapeutic efficacy C) High TPMT levels result in reduced metabolism of 6-MP, leading to D) Low TPMT levels result in increased metabolism of 6-MP, leading to excessive drug accumulation and toxicity.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section: Chapter Questions

Problem 6TYU

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