Outline Knudson’s two-hit hypothesis of retinoblastoma and describe how it helps to explain unilateral and bilateral cases of retinoblastoma.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter12: Genes And Cancer
Section: Chapter Questions
Problem 10QP: Distinguish between dominant inheritance and recessive inheritance in retinoblastoma.
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Outline Knudson’s two-hit hypothesis of retinoblastoma and describe how it helps to explain unilateral and bilateral cases of retinoblastoma.

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