Once an RNA polymerase has initiated transcription, it will release the sigma factor or sigma subunits or bind other proteins known as elongation factors before it begin moving down the DNA template doing strand elongation. Briefly explain why this is necessary - why cant RNA polymerase + sigma factor do all of transcription?

Once an RNA polymerase has initiated transcription, it will release the sigma factor or sigma subunits or bind other proteins known as elongation factors before it begin moving down the DNA template doing strand elongation. Briefly explain why this is necessary - why cant RNA polymerase + sigma factor do all of transcription?

Biology Today and Tomorrow without Physiology (MindTap Course List)

5th Edition

ISBN:9781305117396

Author:Cecie Starr, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Christine Evers, Lisa Starr

Chapter7: Gene Expression And Control

Section: Chapter Questions

Problem 4CT

See similar textbooks

Similar questions

Once an RNA polymerase has initiated transcription, it will release the sigma factor or sigma subunit and bind other proteins known as elongation factors before it begins moving down the DNA template doing strand elongation. Briefly explain why this is necessary - why can't RNA polymerase + sigma factor do all of transcription? Be specific.
Initiation of transcription in prokaryotic cells requires not only RNA polymerase, but also an "initiation factor" called the sigma factor or sigma subunit. Why can't the core RNA polymerase, without its sigma subunit, initiate transcription?
Although initiation requires the sigma factor or sigma subunit be associated with the core RNA polymerase, in order to switch to the elongation phase of transcription, RNA polymerase must release the sigma factor and associate with elongation factors instead. What do these elongation factors do - why are they necessary for the elongation phase of transcription?
Which of the following statements concerning the sequence of events involved in the initiation of transcription by E. coli RNA polymerase are correct? ( can bemore than one) A.)Initiation starts with a pyrimidine nucleotide triphosphate. B.)The sigma factor (σ) functions during initiation of transcription. C.)Initiation starts with a purine nucleotide triphosphate, which is destined to become the 5'-end of RNA. D.)Initiation starts with a purine nucleotide triphosphate, which is destined to become the 3'-end of RNA. E.)RNA polymerase binds to the DNA at a point approximately 35 bp upstream of the start of transcription, at a sequence TTGACA. F.)The sigma factor does not dissociate until RNA elongation is complete.
What is the production of RNA called and what is the enzyme that catalyzes the process?What are the similarities and differences between the transcription process and the repli-cation processes?Concerning their biological function what is the difference between DNA and RNA? Is there any situation in which DNA is made based on a RNA template? If there is,explain with an example how it occurs and state the enzyme involved?What is the difference between plasma membrane and cell wall?
Explain why inserting 5 bp of DNA at the –50 position of a eukaryotic gene decreases the rate of RNA polymerase II transcription initiation to a greater extent than inserting 10 bp at the same site.
Since RNA polymerase has an error rate of 1 / 10^4 nucleotides, and the DNA polymerase has an error rate of 1 / 10^7 nucleotides, can cells tolerate errors made in transcription in comparison to errors made during DNA replication?
A particular mutation in the bacterial sigma factor allows this protein to bind RNA polymerase but prevents it from coming off (detaching) RNA polymerase once it binds. What specific effect will this mutation have on transcription? It will prevent the transcription termination exerted by the Rho protein. It will prevent the formation of closed complexes between RNA polymerase and the promoter. It will prevent the formation of open complexes between RNA polymerase and the promoter. It will prevent the transition from the transcription initiation to the transcription elongation stage. It will prevent the synthesis of abortive RNA transcripts while the RNA polymerase is bound at the promoter.
The phosphorylation of the RNA polymerase II tail is important for the following EXCEPT a.the formation of transcription initiation complex b.RNA processing c.the dissociation of most general transcription factors d.initiation of transcription by RNA polymerase II
Why is the RNA polymerase/RNA/DNA duplex of the RNA polymerizing complex called transcription bubble? What is the local change in Lk, Tw and Wr within the RNA polymerase DNA transcription bubble?
What are the specific steps of eukaryotic transcription? Be sure in your discussion that you include the following terms: template strand, non-template strand, initiation, elongation, termination, promoter region, RNA polymerase, termination signal.
What would be the likely effect of a mutation that prevents s from dissociating from the RNA polymerase core?