Initiation of transcription in prokaryotic cells requires not only RNA polymerase, but also an "initiation factor" called the sigma factor or sigma subunit. Why can't the core RNA polymerase, without its sigma subunit, initiate transcription?
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
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Initiation of transcription in prokaryotic cells requires not only RNA polymerase, but also an
"initiation factor" called the sigma factor or sigma subunit. Why can't the core RNA polymerase,
without its sigma subunit, initiate transcription?
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