One of the first drugs to be approved for use in treatment of acquired immune deficiency syndrome (AIDS) was azi- dothymidine (AZT). Complete the Lewis structure of AZT. A A A A A A B B O O O C C C C N N N N N C C C O C H HH H H H H C H H H OO CH3 a. How many carbon atoms use sp3 hybridization? b. How many carbon atoms use sp2 hybridization? c. Which atom is sp hybridized? d. How many s bonds are in the molecule? e. How many p bonds are in the molecule? f. What is the NONON bond angle in the azide (ON3) group? g. What is the HOOOC bond angle in the side group attached to the five-membered ring? h. What is the hybridization of the oxygen atom in the OCH2OH group?

Question

One of the first drugs to be approved for use in treatment

of acquired immune deficiency syndrome (AIDS) was azi-
dothymidine (AZT). Complete the Lewis structure of AZT.

A
A

A
A

A
A
B
B
O
O
O

C C
C
C
N
N

N
N
N
C
C
C
O C

H
HH
H
H
H
H

C
H
H

H

OO

CH3

a. How many carbon atoms use sp3 hybridization?
b. How many carbon atoms use sp2 hybridization?
c. Which atom is sp hybridized?
d. How many s bonds are in the molecule?
e. How many p bonds are in the molecule?
f. What is the NONON bond angle in the azide (ON3)
group?
g. What is the HOOOC bond angle in the side group
attached to the five-membered ring?
h. What is the hybridization of the oxygen atom in the
OCH2OH group?

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