One type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle. A) What does it mean to inhibit the transport of sodium ions in the loop of Henle? B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter14: The Urinary System
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One type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle.

A) What does it mean to inhibit the transport of sodium ions in the loop of Henle?

B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.

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