OR ROH + or OR I II :0: + :O:

Chemistry
9th Edition
ISBN:9781133611097
Author:Steven S. Zumdahl
Publisher:Steven S. Zumdahl
Chapter22: Organic And Biological Molecules
Section: Chapter Questions
Problem 57E
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Alcohol functions can be protected as tetrahydropyranyl ethers (THPs) by acid-catalyzed addition to dihydropyran according to the equation:

Addition of the alcohol to dihydropyran is regiospecific in that I is formed to the exclusion of II. Suggest a mechanistic reason for the observed regioselectivity.

OR
ROH
+
or
OR
I
II
:0:
+
:O:
Transcribed Image Text:OR ROH + or OR I II :0: + :O:
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