Patients taking metformin are at increased risk of developing lactic acidosis. How does metformin act to Increase this risk? Metformin stimalates the conumption af pyruvate via gluenneogenesis. This in tum stimuates the uptakr of lactic acid by the liver for conversion to Pyrwate Metformin inhibes gluconeogenesin, which preverts tactic acid from being removed from the blood by the ver and being convertnd to pynvate for gluoneogenesis, Thn keadt to inereeted trculating lactik acid. Hetformin stimulatem gycogenesis, which helps remove ecrn glurose from the bloed, kwerng the amunt ef Lectic acid in the blond Meetormin inhbits beta exidanon, which decreate the amourt of gluee rereded and thu reduces the remove of lactic acit from the blood

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter20: Carbohydrates
Section: Chapter Questions
Problem 20.83P
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Patients taking metformin are at increased risk of developing lactic acidosis. How does
metformin act to Increase this risk?
Metformin stimtates the connumption af pyruvate via gluroneogenesis. This in turn stimates the uptakr of
lactic acid by the lver for conversion to pyrvate.
Metformin inhibts gluconeogenesin, which preverts tatic acid from being removed from the blood by the live
grd being comverted to pynvate for guoneogenesis, Thin keodt to increated tircutating tactic acid.
Hetformin stimulatem gycogenesis, which heps retmove ecen glucose from the bloed, Iwerrg the nount of
Lectic acid in the blond.
Metlormin inhbits beta exidation, which decreates the amourt of glunoee reedet and thun reuces the remove
of tactic ecid from the blood.
61
Which chemical formula represents the fatty ncid structure below?
Transcribed Image Text:Patients taking metformin are at increased risk of developing lactic acidosis. How does metformin act to Increase this risk? Metformin stimtates the connumption af pyruvate via gluroneogenesis. This in turn stimates the uptakr of lactic acid by the lver for conversion to pyrvate. Metformin inhibts gluconeogenesin, which preverts tatic acid from being removed from the blood by the live grd being comverted to pynvate for guoneogenesis, Thin keodt to increated tircutating tactic acid. Hetformin stimulatem gycogenesis, which heps retmove ecen glucose from the bloed, Iwerrg the nount of Lectic acid in the blond. Metlormin inhbits beta exidation, which decreates the amourt of glunoee reedet and thun reuces the remove of tactic ecid from the blood. 61 Which chemical formula represents the fatty ncid structure below?
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