PEGylation plays an important role in the formulation of nanoparticle-based therapeutics: mark all statements that are true: After systemic administration nanoparticles can interact with blood components such as apolipoprotein, albumin, fibrinogen, immunoglobulins, opsonins, which tag the nanoparticle for clearance - this is referred to as protein corona PEGylation is an effective strategy to completely shield nanoparticles and avoid any interactions with the body PEGylation is also termed Opsonization of nanoparticles. PEG stands for poly and it is a highly hydrophobic polymer While PEGylated formulations have been approved and are used in the clinic, careful evaluation of safety is important, because recent data indicate prevalence of anti-PEG antibodies in humans
PEGylation plays an important role in the formulation of nanoparticle-based therapeutics: mark all statements that are true: After systemic administration nanoparticles can interact with blood components such as apolipoprotein, albumin, fibrinogen, immunoglobulins, opsonins, which tag the nanoparticle for clearance - this is referred to as protein corona PEGylation is an effective strategy to completely shield nanoparticles and avoid any interactions with the body PEGylation is also termed Opsonization of nanoparticles. PEG stands for poly and it is a highly hydrophobic polymer While PEGylated formulations have been approved and are used in the clinic, careful evaluation of safety is important, because recent data indicate prevalence of anti-PEG antibodies in humans
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PEGylation plays an important role in the formulation of nanoparticle-based therapeutics: mark all statements that are true:
- After systemic administration nanoparticles can interact with blood components such as apolipoprotein, albumin, fibrinogen, immunoglobulins, opsonins, which tag the nanoparticle for clearance - this is referred to as protein corona
- PEGylation is an effective strategy to completely shield nanoparticles and avoid any interactions with the body
- PEGylation is also termed Opsonization of nanoparticles.
- PEG stands for poly and it is a highly hydrophobic polymer
- While PEGylated formulations have been approved and are used in the clinic, careful evaluation of safety is important, because recent data indicate prevalence of anti-PEG antibodies in humans
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