Semi-synthetic and extended-spectrum penicillins have proven more effective than natural penicillins for two of the following reasons: 1-Interfere more effectively with the development of the peptidoglycan layer in cell-walls 2-Are less sensitive to penicillinases than natural penicillins 3-Do not contain the b-lactam ring thus making them less susceptible to b-lactamases 4-Are less susceptible to the development of resistance 5-Have a broader spectrum of activity
Semi-synthetic and extended-spectrum penicillins have proven more effective than natural penicillins for two of the following reasons: 1-Interfere more effectively with the development of the peptidoglycan layer in cell-walls 2-Are less sensitive to penicillinases than natural penicillins 3-Do not contain the b-lactam ring thus making them less susceptible to b-lactamases 4-Are less susceptible to the development of resistance 5-Have a broader spectrum of activity
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 4.2P
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Semi-synthetic and extended-spectrum penicillins have proven more effective than natural penicillins for two of the following reasons:
1-Interfere more effectively with the development of the peptidoglycan layer in cell-walls
2-Are less sensitive to penicillinases than natural penicillins
3-Do not contain the b-lactam ring thus making them less susceptible to b-lactamases
4-Are less susceptible to the development of resistance
5-Have a broader spectrum of activity
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