Please answer part 1A and 1B please I will upvote then with a proper explanation for the correct answer: 1A. Which one of the relationships between mismatch repair proteins and microsatellites is true? A. Mismatch repair mutations are due to microsatellite sequence methylation B. Mismatch repair proteins methylate microsatellite repeats. C. Microsatellite instability is mostly because of onherited mutations in the mismatch repair proteins. D. Mismatch repair proteins correct microsatellite sequences which usually have a high rate of error. 1B. Which of the following would be a good indication that a colon cancer is sporadic instead of due to Lynch syndrome? A. Mucinous/signet cell histology B. Early age at onset C. Loss of MLH1 protein in the tumor D. MLH1 promoter hypermethylation

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
Please answer part 1A and 1B please I will upvote then with a proper explanation for the correct answer:
1A. Which one of the relationships between mismatch repair proteins and microsatellites is true?
A. Mismatch repair mutations are due to microsatellite sequence methylation
B. Mismatch repair proteins methylate microsatellite repeats.
C. Microsatellite instability is mostly because of onherited mutations in the mismatch repair proteins.
D. Mismatch repair proteins correct microsatellite sequences which usually have a high rate of error.
1B. Which of the following would be a good indication that a colon cancer is sporadic instead of due to Lynch syndrome?
A. Mucinous/signet cell histology
B. Early age at onset
C. Loss of MLH1 protein in the tumor
D. MLH1 promoter hypermethylation
Transcribed Image Text:Please answer part 1A and 1B please I will upvote then with a proper explanation for the correct answer: 1A. Which one of the relationships between mismatch repair proteins and microsatellites is true? A. Mismatch repair mutations are due to microsatellite sequence methylation B. Mismatch repair proteins methylate microsatellite repeats. C. Microsatellite instability is mostly because of onherited mutations in the mismatch repair proteins. D. Mismatch repair proteins correct microsatellite sequences which usually have a high rate of error. 1B. Which of the following would be a good indication that a colon cancer is sporadic instead of due to Lynch syndrome? A. Mucinous/signet cell histology B. Early age at onset C. Loss of MLH1 protein in the tumor D. MLH1 promoter hypermethylation
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Mitochondrial mutations
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education