PPH3 NaOCH2CH3 isotretinoin OH но Br

Q: Sharpless epoxidation of allylic alcohol X forms compound Y. Treatmentof Y with NaOH and C6H5SH in…

A: Two different chiral diethyl tartrate isomers, (+)-DET and (-)-DET are used to indicate the…

Q: Sharpless epoxidation of allylic alcohol X forms compound Y. Treatment of Y with NaOH and C6H5SH in…

A: Two different chiral diethyl tartrate isomers, (+)-DET and (-)-DET are used to indicate the…

Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

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Q: Cholic acid, a major constituent of bile, has the structure shown.(a) Draw the structure of cholic…

A: The axial and equatorial positions in chair conformation of cyclohexane are as follows.

Q: The shrub ma huang (Section 5.4A) contains two biologically activestereoisomers—ephedrine and…

A: Since you have posted a question with multiple sub-parts we will solve the first three sub-parts for…

Q: Aspartame, the sweetener used in the commercial products NutraSweet and Equal, is 200 times sweeter…

A: Aspartame is the sweetener that is used in NutraSweet and Equal and it is 200 times more sweetener…

Q: 1.2 The following is a drug used to treat multi-drug resistant strains of Falciparum malaria CH3 H3C…

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Q: Jiadifenin is a natural product isolated from the fruit of the Chinese plant Illicium jiadifengpi,…

A: A stepwise mechanism for the conversion of M to N has to be drawn.

Q: 3. Draw the structure of cyclopentylisopropylamine. Classify it as 1º, 2° or 3°.

A: The structure of cyclopentylisopropylamine is as follows,

Q: What product is formed when the esters in ginkgolide B, the chapter-opening molecule, are hydrolyzed…

A: The hydrolysis of esters in the presence of acid leads to the formation of carboxylic acids and…

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: (a) The given compound A is a hemiacetal. Sodium borohydride (NaBH4) is a strong reducing agent. It…

Q: Compound J, C16H16Br2, is optically active. On treatment with strong base, compounds K and L (each…

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Q: Heating compound X with aqueous formaldehyde forms Y (C17H23NO), which has been converted to a…

A: The above reaction indicates that lone pairs of electron present on the nitrogen atom of given…

Q: Identify C and D in the following reaction scheme, two steps in the synthesis of the…

A: The formation of compound C is shown below.

Q: What happens if ethyl chloride is treated with: a) KOHaq.; b) KCN; c) Mg/ether; d) CH3COONa; e)…

A: Ethyl Chloride has the formula C2H5Cl or CH3CH2Cl where Cl is the most electronegative atom so C of…

Q: Compound A is a derivative of the carbohydrate perosamine, which is found in the antibiotic…

A: Introduction: Antibiotics are drugs that help the body to fight bacterial functions. Antibiotics…

Q: An acid–base reaction of (R)-sec-butylamine with a racemic mixture of 2-phenylpropanoic acid forms…

A: The reaction between racemic mixture of 2 -phenylpropanoic acid with (R) -sec-butylamine is an acid…

Q: Propose a mechanism for the formation of (A)

A: The formation of A goes through a double nucleophilic attack after the 2 eq. of sodium hydride…

Q: Acetylenic fatty acids are found in many tropical plants. Compound H, C13H2502, is one such…

A: Note : Compound H absorbs 5 equivalents of hydrogen. Therefore compound is have two triple bonds and…

Q: Give the expected organic product when phenylacetic acid, PhCH2COOH, is treated with reagent…

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Q: >Nomex, a polyamide used in such applications as fire-retardant clothing, is prepared by reaction…

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Q: Draw the products formed when p-methylaniline (p-CH3C6H4NH2) is treated with each reagent.a. HClb.…

A: a.

Q: Betamethasone is a synthetic anti-inammatory steroid used as a topical cream for itching.…

A: Betamethasone is a steroid. It is mainly used for the itching. It is prepared from cortisol. The…

Q: Give the expected organic product when phenylacetic acid, PhCH2COOH, is treated with reagent…

A: When carboxylic acid reacts with sodium hydroxide there will be a formation of sodium salt of that…

Q: d-Glucuronic acid is found widely in plants and animals. One of its functions is to detoxify…

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Q: Identify the lettered compounds in each reaction sequence.Draw the product formed when…

A: There are many mechanisms in organic chemistry such as nucleophilic substitution, nucleophilic…

Q: d-Glucuronic acid is found widely in plants and animals. One of its functions is to detoxify…

A: Glucuronic acid is an aliphatic cyclic compound with oxygen form a constituent of the ring. Besides,…

Q: Explain each observation: (a) When (R)-2-methylcyclohexanone is treated with NaOH in H2O, the…

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Q: The following structure possesses a carbonyl (C-O) functional group with prochiral 'faces', and a…

A: Structure is viewed from that side from where, Hydrogen in above side.  Above group means the group…

Q: Give the expected organic product when phenylacetic acid, PhCH2COOH, is treated with reagent…

A:

Q: If a 1:1 mixture of ethyl ethanoate and methyl butanoate is treated with base under Claisen…

A: When two ester undergoes condensation reaction is presence of base to give beta keto ester, the…

Q: A key step in the synthesis of the narcotic analgesic meperidine (trade name Demerol) is the…

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Q: Sharpless epoxidation of allylic alcohol X forms compound Y. Treatment of Y with NaOH and C6H5SH in…

A:

Q: Give the expected organic product when phenylacetic acid, PhCH2COOH, is treated with reagent…

A: Given reaction, Phenylacetic acid, PhCH2COOH with NaHCO3, H2O

Q: Sphingomyelins are found in animal cell membranes, especially in the myelin sheath that surrounds…

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Q: b. Identify the common name of the heterocycle, in the following compounds with biological activity…

A: Drug - it is substance  which is  used to prevent or treat to relieve symptoms of a disease.

Q: Aziridines are heterocycles that contain an N atom in a three-membered ring. Like epoxides,…

A: Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir…

Q: When benzyl alcohol is oxidized with KMNO4, the product obtained is which of the following compound?…

A:

Q: a. Draw a three-dimensional structure for the following steroid. b. What is the structure of the…

A: a. In 3D structure, each color represent a specific atom and each line represents each bond present…

Q: Treatment of (HOCH2CH2CH2CH2)2CO with acid forms a product of molecular formula C9H16O2 and a…

A: The given compound in presence of an acid forms the product with molecular formula C9H16O2.

Q: Identify compounds A, B, and C. a.Compound A has molecular formula C8H12 and reacts with two…

A: Compound A – C8H12

Q: Lithiated pyrimidine is an important intermediate in the formation of the fungicide fenerimol. Give…

A:

Q: What product is formed when the esters in ginkgolide B, the chapter-opening molecule, are hydrolyzed…

A: The hydrolysis of esters in the presence of acid leads to the formation of carboxylic acids and…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.