Problem 4: Here are four human pedigrees. The black symbols represent an abnormal phenotype inherited in a simple Mendelian manner. 2 3 5588 bogo ملح 55666 a. For each pedigree, state whether the abnormal condition is dominant or recessive. Try to state the logic behind your answer. b. For each pedigree, describe the genotypes of as many persons as possible.
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- PROBLEM 1. In a certain plant, yellow fruit, Y, is dominant to white fruit, y. A heterozygous plant with yellow fruit is crossed with a plant with white fruit. Determine the probable genotypic and phenotypic ratios resulting from this cross. Determine the probable genotypic and phenotypic ratios expected from crossing two heterozygous plants of Problem 1. Show your complete solutions (Punnet square)Question:- 3. Wild type Drosophila has red eyes and gray body*. Autosomal recessive mutations sepia (se) and ebony (e) modify the eye and body color, respectively. What kind of a cross (or crosses) can you set up to determine whether the two genes are linked? You have several lines to choose from: a pure-breeding wild type line (where alleles for both, sepia and ebony are wild type), a double homozygous recessive line, a pure breeding sepia mutant line and a pure breeding ebony mutant line. You don’t have to use all of them. (a) Write down the cross (or crosses, if necessary) which will allow you to determine linkage; include genotypes of both crossed individuals (b) What kind of results (offspring) do you expect if the two genes are linked? (c) What kind of results (offspring) do you expect if the two genes are not linked? For (b) and (c), state the phenotypes, genotypes and numbers.Problem 4: You are planning an experiment to use zinc finger nucleases to generate a double-stranded DNA break in a targeted sequence of DNA Name the protein domain in a zinc finger nuclease that is responsible for generating the DNA break Fok1 Name two other genome-engineering proteins that could be used for generating the double-stranded DNA break What are the advantages and disadvantages of each strategy?
- Problem 5. The eye color of fruit flies is an X-linked trait. The red eye color is dominant and the white eye color is recessive. If a white-eyed male fly mates with a heterozygous red-eyed female fly, what will be the genotypes and phenotypes of their offspring? a) Construct a Punnett Square - List gametes in the area with the dashed line and the genotypes of the offspring in the area with the sold line. b) Genotypes of Offspring- c) Phenotypes of Offspring-Question: Black hair of the mouse is produced by dominant gene B and white hair by recessive allele b.Female with black hair crossed with male black hair (both genotypes are heterozygous). Produced individuals 112 and 113, female with white hair and male with black hair, then mating occur between 114 and 113, and another mating occur between 112 and 111. assume that 111 and 114 individuals do not carry the recessive allele, represents the above in a pedigree chart and determine the genotype of each individual.Question- 1. In onions, male sterility is due to the interaction of a chromosomal allele pair hh and “sterile” (S) cytoplasm. All other combinations (i.e. HH/Hh and “sterile” cytoplasm, HH/Hh or hh “fertile” (F) cytoplasm) result in male-fertile plants. The male-sterile trait is incorporated into inbred lines to produce hybrid F1 seed on a commercial scale.a) How would you perpetuate the male-sterile line? Show the cross.b) Briefly outline the method of producing hybrid seed (heterozygote) for the commercial crop. Show the cross.c) Does it matter whether the cytoplasm is fertile or sterile in the male-fertile inbred? Explain.
- Question #1 a. Explain why there is a non-Mendelian 2:1 yellow/agouti phenotypic ratio in this cross. b. What is the Raly gene? What does it encode? How does it relate to the lethality of Ay? c. A heterozygous mouse AAy does not produce enough pigment and it is yellow. Homozygous individuals die during development, but AAy heterozygous do not. Why? You may use any graphic aid to explain this, if necessary. This means that you may use a Punnett square or a forking segregation diagram, or computations with fractions.Question 1: In tomatoes, round fruit (O) is dominant to oblong fruit (o). Write as much as possible of the genotypes of: (A) A plant from a homozygous round-fruited stock (B) A plant from an oblong strain (C) A round-fruited plant which resulted from a testcross (D) A oblong-fruited plant which resulted from the cross of two round-fruited ones.Problem 1. A male black (BB) and polled (PP) Angus is crossed with a female black (BB) and horned (pp) Angus. Give the phenotypic and genotypic ratio of their F1 offspring. Problem 2. If the F1 in Problem 1 is inter se mated, what are the possible phenotypic and genotypic ratios of their offspring? Please Show your answer In punnet square and step by step solution
- Sample problems related to non Mendelian inheritanceRead, analyze and answer completely the following problems: 1. Explain why it is possible for the proband in the following pedigree to have children of blood types A, B, and AB. Considering epistatic genes, what are the possible genotypes of II-2? 2. Agouti (A) is wild type and produces alternating bands of pigment on each hair. Black (a) is recessive to agouti. A mutation on gene B (recessive b) can eliminate all color. In a cross between agouti (AABB) and albino (aabb) mice, what genotypes, phenotypes, and proportions are expected in the offspring in F1 and F2 generations?QUESTION 5. The pedigree below follows the appearance of a rare autosomal dominant condition resulting in malformation of limbs through a family. What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)? Enter your answer in the form of a fraction without any spaces. e.g., If your answer is “one-fourth”, enter: 1/4Problem 4: In Andalusian fowls, the heterozygous condition for the alleles of black plumage and white plumage is blue plumage. What offspring will a blue Andalusian rooster have if bred to birds of the following plumage: black plumage blue plumage white plumage Diagram the three crosses. List the probability of each of the three types of plumage occurring.