Propose steps for the following conversions using a reaction of a diazonium salt in at least one step of each conversion. Q.) Toluene to 4-fluorobenzoic acid
Propose steps for the following conversions using a reaction of a diazonium salt in at least one step of each conversion. Q.) Toluene to 4-fluorobenzoic acid
Macroscale and Microscale Organic Experiments
7th Edition
ISBN:9781305577190
Author:Kenneth L. Williamson, Katherine M. Masters
Publisher:Kenneth L. Williamson, Katherine M. Masters
Chapter16: The Sn2 Reaction: 1-bromobutane
Section: Chapter Questions
Problem 1Q: Which experimental method would you recommend for the preparation of 1-bromooctane and of t-butyl...
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Question
Propose steps for the following conversions using a reaction of a diazonium salt in at least one step of each conversion.
Q.) Toluene to 4-fluorobenzoic acid
Expert Solution
Step 1
Here we have to prepare 4-fluorobenzoic acid from toluene, this conversion including the following steps:
- Nitration.
- Reduction.
- Diazotisation.
- Oxidation.
Step 2
(Toluene) (4-nitrotoluene) (4-methylnitroaniline)
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