Q. Because you love to work with children, you accept a job offer at a local pediatric clinic. A concerned mother brings her daughter who had eye infection (pink eye, caused by gram-negative bacteria). The doctor prescribes her Cephalosporin antimicrobial drug. After a few days, the mother returned to the clinic and complained that the medicine did not help her daughter. This time, the physician prescribes Penicillin antimicrobial drugs. However, based on your knowledge in microbiology class answer: 1) why Cephalosporins does not eliminate the bacteria?  2) why do you think the Penicillin antimicrobial drugs will not help the little girl, and the physician should prescribe a Streptomycin antimicrobial drug as eye drops?  3) If the same bacteria develop resistance to Streptomycin, describe the bacteria's possible resistance method against this antimicrobial drug?

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter7: Basic Clinical Microbiology
Section7.1: Introduction To Clinical Microbiology
Problem 13RQ
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Q. Because you love to work with children, you accept a job offer at a local pediatric clinic. A concerned mother brings her
daughter who had eye infection (pink eye, caused by gram-negative bacteria). The doctor prescribes her Cephalosporin
antimicrobial drug. After a few days, the mother returned to the clinic and complained that the medicine did not help her
daughter. This time, the physician prescribes Penicillin antimicrobial drugs. However, based on your knowledge in
microbiology class answer:
1) why Cephalosporins does not eliminate the bacteria? 
2) why do you think the Penicillin antimicrobial drugs will not help the little girl, and the physician should prescribe a
Streptomycin antimicrobial drug as eye drops? 
3) If the same bacteria develop resistance to Streptomycin, describe the bacteria's possible resistance method against this
antimicrobial drug?

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