Q.A3 (a) The biological tissues are complex, anisotropic conductors with resistive and reactive components. Fig. A3a below shows the distribution of cells in a tissue with all the relevant components shown including cell membrane (CM), extra-cellular fluid (RE) and intra-cellular fluid (R1). For such a tissues low-temperature cryopreservation employing slow-freezing and fast-thawing is considered as a viable method for the long-term preservation. However, the freezing and thawing processes themselves can induce injuries to the cells and tissue by damaging the structure and consequently functionality of the cryopreserved tissue. Bio-impedance measurements have been proposed as non-invasive method to evaluate the extent of thawing. Cell Membrane Extra-Cellular Fluid (ECF) Intra-Cellular Fluid (ICF) Fig. A3a: Schematic of cell distribution inside a tissue

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 14P
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Under fully thawed conditions,what path will the low frequency current take and why?
purpose of each step made towards the solution of the glven questlon. Indicate any assumptlons
made. Also, clearly Indicate the units assoclated with any varlables Involved In your solutions.
SImply answering questlons wlthout presenting the worklng out wlll not be accepted.
Q.A3
(a)
The biological tissues are complex, anisotropic conductors with resistive and
reactive components. Fig. A3a below shows the distribution of cells in a tissue with
all the relevant components shown including cell membrane (CM), extra-cellular
fluid (RE) and intra-cellular fluid (R1). For such a tissues low-temperature
cryopreservation employing slow-freezing and fast-thawing is considered as a viable
method for the long-term preservation. However, the freezing and thawing processes
themselves can induce injuries to the cells and tissue by damaging the structure and
consequently functionality of the cryopreserved tissue. Bio-impedance
measurements have been proposed as non-invasive method to evaluate the extent of
thawing.
Cell Membrane
Extra-Cellular
Fluid (ECF)
Intra-Cellular
Fluid (ICF)
Fig. A3a: Schematic of cell distribution inside a tissue
Transcribed Image Text:purpose of each step made towards the solution of the glven questlon. Indicate any assumptlons made. Also, clearly Indicate the units assoclated with any varlables Involved In your solutions. SImply answering questlons wlthout presenting the worklng out wlll not be accepted. Q.A3 (a) The biological tissues are complex, anisotropic conductors with resistive and reactive components. Fig. A3a below shows the distribution of cells in a tissue with all the relevant components shown including cell membrane (CM), extra-cellular fluid (RE) and intra-cellular fluid (R1). For such a tissues low-temperature cryopreservation employing slow-freezing and fast-thawing is considered as a viable method for the long-term preservation. However, the freezing and thawing processes themselves can induce injuries to the cells and tissue by damaging the structure and consequently functionality of the cryopreserved tissue. Bio-impedance measurements have been proposed as non-invasive method to evaluate the extent of thawing. Cell Membrane Extra-Cellular Fluid (ECF) Intra-Cellular Fluid (ICF) Fig. A3a: Schematic of cell distribution inside a tissue
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