Q.A3 (a) The biological tissues are complex, anisotropic conductors with resistive and reactive components. Fig. A3a below shows the distribution of cells in a tissue with all the relevant components shown including cell membrane (CM), extra-cellular fluid (RE) and intra-cellular fluid (R1). For such a tissues low-temperature cryopreservation employing slow-freezing and fast-thawing is considered as a viable method for the long-term preservation. However, the freezing and thawing processes themselves can induce injuries to the cells and tissue by damaging the structure and consequently functionality of the cryopreserved tissue. Bio-impedance measurements have been proposed as non-invasive method to evaluate the extent of thawing. Cell Membrane Extra-Cellular Fluid (ECF) Intra-Cellular Fluid (ICF) Fig. A3a: Schematic of cell distribution inside a tissue
Q.A3 (a) The biological tissues are complex, anisotropic conductors with resistive and reactive components. Fig. A3a below shows the distribution of cells in a tissue with all the relevant components shown including cell membrane (CM), extra-cellular fluid (RE) and intra-cellular fluid (R1). For such a tissues low-temperature cryopreservation employing slow-freezing and fast-thawing is considered as a viable method for the long-term preservation. However, the freezing and thawing processes themselves can induce injuries to the cells and tissue by damaging the structure and consequently functionality of the cryopreserved tissue. Bio-impedance measurements have been proposed as non-invasive method to evaluate the extent of thawing. Cell Membrane Extra-Cellular Fluid (ECF) Intra-Cellular Fluid (ICF) Fig. A3a: Schematic of cell distribution inside a tissue
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 14P
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Under fully thawed conditions,what path will the low frequency current take and why?
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