Question 2: DNA repair enzymes preferentially repair mismatched bases on the newly synthesized DNA strand, using the old DNA strand as a template. If mismatches were instead repaired without regard for which strand should serve as template, would mismatch repair reduce the number of errors made during replication (as compared to no repair at all)? Would such a mismatch repair system result in fewer total errors, more errors, or the same number of errors as compared to a cell with no repair mechanism at all? (Hint: You may want to consider how many correct and incorrect pieces of DNA there are in each situation post replication.) Carefully explain your answers.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question 2: DNA repair enzymes preferentially repair mismatched bases on the newly synthesized
DNA strand, using the old DNA strand as a template. If mismatches were instead repaired without
regard for which strand should serve as template, would mismatch repair reduce the number of errors
made during replication (as compared to no repair at all)? Would such a mismatch repair system result
in fewer total errors, more errors, or the same number of errors as compared to a cell with no repair
mechanism at all? (Hint: You may want to consider how many correct and incorrect pieces of DNA
there are in each situation post replication.) Carefully explain your answers.
Transcribed Image Text:Question 2: DNA repair enzymes preferentially repair mismatched bases on the newly synthesized DNA strand, using the old DNA strand as a template. If mismatches were instead repaired without regard for which strand should serve as template, would mismatch repair reduce the number of errors made during replication (as compared to no repair at all)? Would such a mismatch repair system result in fewer total errors, more errors, or the same number of errors as compared to a cell with no repair mechanism at all? (Hint: You may want to consider how many correct and incorrect pieces of DNA there are in each situation post replication.) Carefully explain your answers.
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