A researcher sequences the Pitx1 gene in a population of 100 stickleback fish that is known to affect dorsal spine length. He finds that the gene is NOT in Hardy-Weinberg equilibrium. There is an excess of homozygotes compared to expected. He then sequences 5 more loci scattered across the genome (on different chromosomes) but finds that these other loci are all in HW equilibrium. (That is, there was no difference between observed and expected frequencies). What is the most reasonable conclusion concerning the Pitx1 gene?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...
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A researcher sequences the Pitx1 gene in a population of 100 stickleback fish that is known to affect dorsal spine length. He finds that the gene is NOT in Hardy-Weinberg equilibrium. There is an excess of homozygotes compared to expected. He then sequences 5 more loci scattered across the genome (on different chromosomes) but finds that these other loci are all in HW equilibrium. (That is, there was no difference between observed and expected frequencies). What is the most reasonable conclusion concerning the Pitx1 gene?

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