Question 26 Predict the FINAL (?) product (or a mixture of products) for the following synthetic transformation: до NASH DMSO Br two diastereomers A B C D SN2 t-BuOK 1. OsO4 2. H₂O2 ? Br2 Hofmann product H₂ Pd catalyst two diastereomers A B с D

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter18: Functional Derivatives Of Carboxylic Acids
Section: Chapter Questions
Problem 18.55P: In Problem 7.28, we saw this step in Johnsons synthesis of the steroid hormone progesterone. Propose...
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Question 26
Predict the FINAL (?) product (or a mixture of products) for the following synthetic transformation:
до
NASH
DMSO
Br
two diastereomers
A
B
C
D
SN2
t-BuOK
1. OsO4
2. H₂O2
?
Br2
Hofmann product
H₂
Pd catalyst
two diastereomers
A
B
с
D
Transcribed Image Text:Question 26 Predict the FINAL (?) product (or a mixture of products) for the following synthetic transformation: до NASH DMSO Br two diastereomers A B C D SN2 t-BuOK 1. OsO4 2. H₂O2 ? Br2 Hofmann product H₂ Pd catalyst two diastereomers A B с D
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