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- QUESTION 28 Which of the following is the primary method by which cyclin proteins are regulated to influence entry into the cell cycle or transition from one stage to the next? A. Transcriptional upregulation and translation followed by targeted ubiquitin-mediated degradation by a proteasome. B. Phosphorylation to regulate the activity of the kinase site. C. An activating phosphorylation and an inactivating phosphorylation. D. All of these are mechanisms that can be used to regulate cyclins.QUESTION 29 Which of the following is NOT a primary method used to regulate the activity of cyclin-dependent kinases (cdks)? A. Binding to cyclins B. Binding to a CDK inhibitor C. Dephosphorylation of a specific amino acid D. Degradation by a proteasome E. Phosphorylation on a specific amino acidQuestion:- where do each of thse go? which box
- iPSCs are derived from differentiated cells that are further differentiated into a stem cell state. True or false?What are some of the ethical issues that arise from using embryonic stem cells?(b) To avoid these issues, scientists use IPSCs. What are the pros and cons to using iPSCs inrelation to embryonic stem cells?QUESTION 49 Which of the following is not true/accurate with respect to p53? a. is a tumor-suppressor b. is a transcription factor that promotes transcription of inhibitors of the cell cycle c. is an oncogene d. is named for its molecular mass (in kiloDaltons)
- Question 16 Which of the following is not considered as a requirements for the effective binding and translocation of proteins into the ER? signal sequence in the newly synthesized polypeptide GDP SRP and SRP receptor TransloconQUESTION 4 Which of the following G protein subunits activate K+ channels in response to the GPCR for acetylcholine on heart muscle? a. Galpha inhibitory. b. G alpha stimulatory c. G beta gamma dimer. d. G alpha transducin.Descrive in 2-3 sentences an in vitro experiment that differentiates between the Arp2/3 complex’ ability to associate with both the side of the ‘mother’ actin filament and with the barbed end of the ‘mother’ actin filament. Your experiment should take advantage of capping protein (binds and blocks barbed ends), and direct visualization of actin filaments.
- Adult stem cells, such as those in the bone marrow, brain, or hair follicles, can best be described as ______, whereas embryonic stem cells are described as ______. a. totipotent; pluripotent b. pluripotent; multipotent c. multipotent; pluripotent d. totipotent; multipotentDichotomous key:a. Convert the following dichotomous key into the flowchart version as described in Fig. 10.5 of your text. please refer to attached photo.Can you please help me with question( 9) 5. In the film, Dr. Jablonski explains that melanin, located in the top layer of human skin, absorbs UV radiation, protecting cells from the damaging effects of UV. Genetics determines the type of melanin (i.e., brown/black eumelanin or red/brown pheomelanin) and the amount of melanin present in an individual’s cells. Based on this information, write a hypothesis for where in the world you would expect to find human populations with darker or lighter skin pigmentation (i.e., different amounts of melanin). 9. Do these data support your hypothesis from Question 5? Justify your answer.