Regarding TLC plates: a) When spotting a TLC plate, are small spots or large spots better? Or does the size of the spots not matter? b) Do separation of compounds on a TLC plate depends primarily on polarity, boiling point, molecular weight, melting point, or density?

Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter10: Fuels, Organic Chemicals, And Polymers
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Regarding TLC plates: a) When spotting a TLC plate, are small spots or large spots better? Or does the size of the spots not matter? b) Do separation of compounds on a TLC plate depends primarily on polarity, boiling point, molecular weight, melting point, or density?
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