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Relate the successful use of oral rehydration therapy to the pathogenesis
of cholera.
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- Compare the mechanism of virulence for Vibrio cholerae and enterotoxigenic E.coli. Specifically, how do these bacteria bind to host cells and what factors are involved in producing the diarrhea observed in infected patients?Describe the major features of how cholera toxin damages intestinal cells.How can we prove the pathological and clinical effects of cholera are caused by the production of enterotoxin?
- Identify two virulence factors in the picture and explain, in detail, how they mediate V. cholerae pathogenesis.Regarding CHOLERA Briefly give the - causative agent - transmission - signs and symptoms - portal of entry and exit - management (prevention and treatment).Explain how Vibrio cholerae causes cholera.
- The general public takes for granted the link between an infectious agent and a given infection Discuss the requirements established by Koch, the nineteenth-century German scientist, before ascertaining, for instance, that Helicobacter pylori bacterium is the cause of the gastric ulcer. Why is it so essential to meet these conditions?. Describe how one could break the chain of infection for cholera, such as breaking the pathogen link, by providing a specific intervention.Describe how you will demonstrate the Koch's postulate in linking Buruli Ulcer to its causative organism