Retrosynthetic Analysis Question In the box draw the two possible starting materials you could use to synthesize the following molecules using the reaction indicated. Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction Nucleophilic Subsitution Reaction followed Acid Catalyzed Hydration of Alkyne Nucleophilic Subsitution Reaction followed by hydroboration Oxidation of Alkyne
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- This is Wittig Rxn: Whatever mechanism you choose to draw is fine since you can leave the base as B: Draw the arrow pushing mechanism using the compounds below – Constant: 4-nitrobenzyl benzaldehydebase 1: triethylaminebase 2: NaOHbase 3: K2CO3ylide: Acetonyltriphenylphosphonium chloridePropose how you could synthesize the following compound, using a substitution reaction. Propose a nucleophile, a solvent, and an electrophile. Show the curved-arrow mechanism of the reaction. Finally, draw the transition state of the reaction.Indicate which of the ff. statements regarding nucleophilicity is incorrect. 1. F- is more nucleophilic, hence, more reactive towards methyl iodide than Cl-. 2. Second-row elements are more nucleophilic than first-row elements of comparable basicity. 3. Nucleophilicity is the affinity of a nucleophile to an electrophilic carbon. 4. The rate of SN2 reaction may be markedly affected by the nucleophilicity of the attacking atom
- Rank the nucleophiles in following group in order of increasing nucleophilicity. −OH, Br−, F− (polar aprotic solvent)Using the diagram below, answer the ff. questions.1. What pattern of curved arrow pushing is the second step of this reaction?a. loss of a leaving groupb. proton transferc. rearrangement 2. What pattern of curved arrow pushing is the fourth step of this reaction?a. proton transferb. loss of a leaving groupc. nucleophilic attackConsider the mechanism of a reaction below Aniline (with NH2) above acts as ____________________ Lewis base and a nucleophile Lewis acid and a nucleophile Lewis base and an electrophile Lewis acid and an electrophile none of the above Draw a RESONANCE STRUCTURE (major contributor please) of the product. Please use curved arrows to push electrons:
- Draw the structure(s) of the major product(s) of the following reaction after workup to neutralize acid. You do not have to consider stereochemistry. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Include the counterion when the product is a quaternary ammonium salt. Draw the counterion in its own sketcher. Separate multiple products using the + sign from the drop-down menu. If no reaction occurs, draw all starting materials.Synthesis: A Hormone Herbicide please draw the molecules and explain 1. Draw benzene + methanol + acid catalysis = Hormone Herbicide intermediate 1. 2. Draw Hormone Herbicide intermediate 1 + fuming sulfuric acid + heat + time = Hormone Herbicide intermediate 2. 3. Draw Hormone Herbicide intermediate 2 + HNO3/H2SO4 + heat = Hormone Herbicide intermediate 3. 4. Draw Hormone Herbicide intermediate 3 + water + heat = Hormone Herbicide intermediate 4.5. Draw Hormone Herbicide intermediate 4 + H2/Pd = Hormone Herbicide intermediate 5.6. Draw Hormone Herbicide intermediate 5 + NaNO2/HCl = Hormone Herbicide intermediate 6.7. Draw Hormone Herbicide intermediate 6 + CuOH = Hormone Herbicide intermediate 7. 8. Draw Hormone Herbicide intermediate 7 + Cl2/FeCl3 = Hormone Herbicide intermediate 8.9. Draw Hormone Herbicide intermediate 8 + NaOH = Hormone Herbicide intermediate 9.10. Draw Hormone Herbicide intermediate 9 + 2-chloroethanoic acid = A Hormone Herbicide.Synthesis: A Hormone Herbicide. Please draw the molecules and explain 1. Draw benzene + methanol + acid catalysis = Hormone Herbicide intermediate 1. 2. Draw Hormone Herbicide intermediate 1 + fuming sulfuric acid + heat + time = Hormone Herbicide intermediate 2. 3. Draw Hormone Herbicide intermediate 2 + HNO3/H2SO4 + heat = Hormone Herbicide intermediate 3. 4. Draw Hormone Herbicide intermediate 3 + water + heat = Hormone Herbicide intermediate 4.5. Draw Hormone Herbicide intermediate 4 + H2/Pd = Hormone Herbicide intermediate 5.6. Draw Hormone Herbicide intermediate 5 + NaNO2/HCl = Hormone Herbicide intermediate 6.7. Draw Hormone Herbicide intermediate 6 + CuOH = Hormone Herbicide intermediate 7. 8. Draw Hormone Herbicide intermediate 7 + Cl2/FeCl3 = Hormone Herbicide intermediate 8.9. Draw Hormone Herbicide intermediate 8 + NaOH = Hormone Herbicide intermediate 9.10. Draw Hormone Herbicide intermediate 9 + 2-chloroethanoic acid = A Hormone Herbicide EXPLAIN PLEASE!
- select the most appropriate reagent(s) to effect the change. K2Cr2O7, H+ H2, Pd 1. Disiamylborane, 2. HO–, H2O, H2O2 NaOCl H2SO4, HgSO444. Sterically hindered bases produce what is the major product? Zaitsev product Hoffman product Markovnikov product Anti-Markovnikov productA4 Express the retro synthesis scheme using the suggested starting material (SM) for the following target compound (TM). After performing the retro synthesis analysis, synthesize the target compound according to the analyzed scheme.