rotein kinase inhibitors have become a major focus for the development of molecularly targeted cancer therapies. Based on what you know from the development of Gleevec, what are at least two generalizable principles that apply to the development of all tyrosine kinase inhibitors? What is a potential pitfall of targeting a protein kinase for cancer treatment? (Relate back to Gleevec example - this answer should include three separate concepts – 2 principles, 1 limitation)
rotein kinase inhibitors have become a major focus for the development of molecularly targeted cancer therapies. Based on what you know from the development of Gleevec, what are at least two generalizable principles that apply to the development of all tyrosine kinase inhibitors? What is a potential pitfall of targeting a protein kinase for cancer treatment? (Relate back to Gleevec example - this answer should include three separate concepts – 2 principles, 1 limitation)
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter6: Cell Communication
Section: Chapter Questions
Problem 11TYU: More than 500 genes have been identified in the human genome that code for protein kinases. What...
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Protein kinase inhibitors have become a major focus for the development of molecularly targeted cancer therapies. Based on what you know from the development of Gleevec, what are at least two generalizable principles that apply to the development of all tyrosine kinase inhibitors? What is a potential pitfall of targeting a protein kinase for cancer treatment? (Relate back to Gleevec example - this answer should include three separate concepts – 2 principles, 1 limitation)
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