salicylic acid acetic acid acetylsalicylic acid (aspirin)

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter18: Carboxylic Acids
Section: Chapter Questions
Problem 18.10P
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What type of reaction is this? It looks like some sort of Williamson Ether-looking synthesis, but involving phenols? How does the mechanism of this work? 

OH
C-OH
salicylic acid
+ CH₂-C-OH
acetic acid
H+
C
-C-CH₂
-ОН
acetylsalicylic acid
(aspirin)
+ H₂O
Transcribed Image Text:OH C-OH salicylic acid + CH₂-C-OH acetic acid H+ C -C-CH₂ -ОН acetylsalicylic acid (aspirin) + H₂O
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