SCENARIO 1: A study was undertaken to compare clinical superiority between a new investigational drug and the standard of care drug. 300 participants total were enrolled. Participants were randomized in a 2:1 fashion to receive the investigational drug vs the standard of care drug. Of those receiving the investigational drug, 44% reported clinical improvement compared to 60% in the standard of care group. Complete the 2 x 2 Contingency table using information summarized in the study above to answer the question below: Exposure Yes No a. 40 O b. 60 C. 88 O d 112 Totals: Yes a C a+c Outcome No b d b+d How many participants receiving the standard of care drug had clinical improvement? Totals: a+b c+d Total participants

MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
SCENARIO 1: A study was undertaken to compare clinical superiority between a new investigational
drug and the standard of care drug. 300 participants total were enrolled. Participants were randomized in
a 2:1 fashion to receive the investigational drug vs the standard of care drug. Of those receiving the
investigational drug, 44% reported clinical improvement compared to 60% in the standard of care group.
Complete the 2 x 2 Contingency table using information summarized in the study above to answer
the question below:
Exposure
Yes
No
a. 40
O b. 60
O c. 88
Totals:
d. 112
Yes
a
C
a+c
Outcome
No
b
d
b+d
How many participants receiving the standard of care drug had clinical improvement?
Totals:
a+b
c+d
Total participants
Transcribed Image Text:SCENARIO 1: A study was undertaken to compare clinical superiority between a new investigational drug and the standard of care drug. 300 participants total were enrolled. Participants were randomized in a 2:1 fashion to receive the investigational drug vs the standard of care drug. Of those receiving the investigational drug, 44% reported clinical improvement compared to 60% in the standard of care group. Complete the 2 x 2 Contingency table using information summarized in the study above to answer the question below: Exposure Yes No a. 40 O b. 60 O c. 88 Totals: d. 112 Yes a C a+c Outcome No b d b+d How many participants receiving the standard of care drug had clinical improvement? Totals: a+b c+d Total participants
Expert Solution
steps

Step by step

Solved in 3 steps

Blurred answer
Recommended textbooks for you
MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc
Probability and Statistics for Engineering and th…
Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning
Statistics for The Behavioral Sciences (MindTap C…
Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning
Elementary Statistics: Picturing the World (7th E…
Elementary Statistics: Picturing the World (7th E…
Statistics
ISBN:
9780134683416
Author:
Ron Larson, Betsy Farber
Publisher:
PEARSON
The Basic Practice of Statistics
The Basic Practice of Statistics
Statistics
ISBN:
9781319042578
Author:
David S. Moore, William I. Notz, Michael A. Fligner
Publisher:
W. H. Freeman
Introduction to the Practice of Statistics
Introduction to the Practice of Statistics
Statistics
ISBN:
9781319013387
Author:
David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:
W. H. Freeman