Select the word from the dropdown menu that correctly completes each of the following statements.
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![Select the word from the dropdown menu that correctly completes
each of the following statements.
The citric acid cycle is also called the
cycle.
V( Choose ]
a-ketoglutarate
aconitase
Krebs
is the first compound that is
oxidized in the citric acid cycle.
malate synthase
malate dehydrogenase
isocitrate
succinyl-CoA synthetase
catalyzes a substrate-level
phosphorylation reaction within the oxaloacetate
citric acid cycle.
malate
succinate dehydrogenase
carbon dioxide
is used in the first reaction of malonate
the citric acid cycle and regenerated
upon completion of one turn of the
citric acid cycle.
A membrane-bound enzyme of the
citric acid cycle that catalyzes
[Choose ]
formation of a trans alkene
dicarboxlic acid product.
The enzyme is unique because
Choose)
it contains an iron-sulfur cluster but
does not participate in a redox
reaction.
The product of a hydration reaction,
this intermediate is always generated
in its L-enantiomeric form.
[Choose
This citric acid cycle enzyme
( Choose)
produces oxaloacetate.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb581fbca-ec51-4760-90b0-29a12a58c2d8%2Fa45178ca-508e-40a9-8ed5-2e678dbb9768%2Feu2d54_processed.jpeg&w=3840&q=75)
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- Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.Ethanol as a Source of Metabolic Energy (Integrates with Chapters 19 and 20.) Acetate produced in ethanol metabolism can be transformed into acetyl-COA by the acetyl thiokinase reaction: Acetate+ATP+CoASHacetyleCoA+AMP+PPiAcetyle-CoA then can enter the citric acid cycle and undergo oxidation to 2 CO2by this route, assuming oxidative phosphorylation is part of the process? (Assume all reactions prior to acetyl-CoA entering the citric acid cycle occur outside the mitochondrion). Per carbon atom, which is a better metabolic fuel, ethanol or glucose? That is, how many ATP equivalents per carbon atom are generated by combustion of glucose versus ethanol to CO2?
- CHOOSE THE CORRECT LETTER 1.Which of the following enzymes catalyze the reaction involved in the production of FADHy in the Kreb's cycle?A. malate dehydrogenaseB. a-ketoglutarate dehydrogenaseC.isocitrate dehydrogenaseD. succinate dehydrogenase 2.Steric acid requires eight cycles of B-oxidation to be completely converted to acety/-CoA.A.TrueB. FalsePlease choose the right answer from the bold text In the malate dehydrogenase-catalyzed reaction, L-malate is (oxidized, unaffected, reduced) to oxaloacetate. Based on their oxidation states, we know that (malate, oxaloacetate, neither) contains more free energy, and free energy will be (released, required) in the forward reaction of malate to oxaloacetate.CHOOSE THE CORRECT LETTER 1.Stearic acid requires eight cycles of B-oxidation to be completely converted to acetyl-CoA.A. TrueB. False 2.ATP is produced from the electron transport system via oxidative phosphorylation.A. TrueB. False
- Choose all the enzymes or enzyme systems of the citric acid cycle that could be classified as oxidoreductases. (Select all that apply.) succinate dehydrogenase aconitase isocitrate dehydrogenase α-ketoglutarate dehydrogenase complex citrate synthase fumarase malate dehydrogenaseWhich of the following citric acid cycle enzymes catalyzes substrate-level phosphorylation? A) isocitrate dehydrogenase B) α-ketoglutarate dehydrogenase C) succinyl CoA synthetase D) succinate dehydrogenase E) malate dehydrogenaseEach of the following citric acid cycle enzymes catalyzes electron transfer to NADH/FADH2 except A) isocitrate dehydrogenase. B) α-ketoglutarate dehydrogenase. C) succinyl CoA synthetase. D) succinate dehydrogenase. E) malate dehydrogenase.
- The acyl-CoA dehydrogenase deficiency diseases are a groupof inherited defects that impair the b-oxidation of fatty acids.Symptoms of the disease range from nausea and vomiting tofrequent comas. Symptoms may be alleviated by eating regularly and avoiding periods of starvation (12 hours or more).Why does this simple procedure alleviate the symptoms?Indicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of the metabolic pathway in the given conditions a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesisIdentify the Krebs cycle enzyme that consumes a 3-carbon substrate molecule, producing a 2- carbon product molecule (attached to acetyl-CoA), along with NADH, and one molecule of CO2. succinyl CoA synthetase a-ketoglutarate dehydrogenase pyruvate dehydrogenase isocitrate dehydrogenase malate dehydrogenase